Trait Mindfulness Predicts Attentional and Autonomic Regulation of Alcohol Cue-Reactivity
Trait Mindfulness Predicts Attentional and Autonomic Regulation of Alcohol Cue-Reactivity
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DOI：
10.1027/0269-8803/a000060
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发表时间：
2011-01-01
影响因子：
1.3
通讯作者：
Garland, Eric L.
中科院分区：
文献类型：
--
作者：
Garland, Eric L.
在没有冥想经验的个体中，正念的特征各不相同，并且与注意力和自主调节有关，这两种神经认知功能在成瘾时会受损。假设具有相对高水平特质正念的酒精依赖住院患者会从压力启动的酒精提示中表现出显著的自主神经恢复，这些提示由更大的注意力脱离介导。58名酒精依赖住院患者参与了情感调节心理生理线索反应方案和空间线索任务，旨在评估酒精注意偏倚（AB）。通过多变量通径分析，研究了特质正念、酒精AB和自主神经活动指数高频心率变异性（HFHRV）之间的关联。较高的特质正念与较低的抵抗饮酒冲动的难度和较强的HFHRV从压力启动的酒精线索中恢复显著相关。在统计控制了正念与感知到的抵抗饮酒冲动困难的相关性后，正念与HFHRV恢复之间的关联部分由酒精线索的注意脱离介导（模型R-2 = 0.30）。正念较高的酒精依赖住院患者能够更好地将注意力从酒精线索中分离出来，这反过来又预测了HFHRV从这些线索中恢复的程度。特质正念可能反映了对食欲反应的认知控制，反映在优越的注意力和压力引发的酒精线索反应的自主调节中。
The trait of mindfulness varies among meditation-naive individuals and is associated with attentional and autonomic regulation, two neurocognitive functions that become impaired in addiction. It was hypothesized that alcohol dependent inpatients with comparatively high levels of trait mindfulness would exhibit significant autonomic recovery from stress-primed alcohol cues mediated by greater attentional disengagement from such cues. Fifty-eight alcohol dependent inpatients participated in affect-modulated psychophysiological cue-reactivity protocol and a spatial cueing task designed to assess alcohol attentional bias (AB). Associations between trait mindfulness, alcohol AB, and an index of autonomic activity, high-frequency heart rate variability (HFHRV), were examined via multivariate path analysis. Higher trait mindfulness was significantly associated with less difficulty resisting the urge to drink and greater HFHRV recovery from stress-primed alcohol cues. After statistically controlling for the correlation of mindfulness and perceived difficulty resisting drinking urges, the association between mindfulness and HFHRV recovery was partially mediated by attentional disengagement from alcohol cues (model R-2 = .30). Alcohol dependent inpatients higher in mindfulness are better able to disengage attention from alcohol cues, which in turn predicts the degree of HFHRV recovery from such cues. Trait mindfulness may index cognitive control over appetitive responses reflected in superior attentional and autonomic regulation of stress-primed alcohol cue-reactivity.