Changes in protein synthesis underlying functional plasticity in immature monkey visual system.

Changes in protein synthesis underlying functional plasticity in immature monkey visual system.
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未成熟猴子视觉系统功能可塑性的蛋白质合成变化。

DOI:
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发表时间:
1981
影响因子:
11.1
通讯作者:
L. Sokoloff
L. Sokoloff
中科院分区:
综合性期刊1区
文献类型:
--
作者:
C. Kennedy;S. Suda;C. Smith;M. Miyaoka;M. Ito;L. Sokoloff

文献摘要

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在急性或慢性单眼视觉剥夺的新生恒河猴中测定了局部脑蛋白质合成率。慢性单眼剥夺导致蛋白质合成率下降,而蛋白质合成率正常膝状体层神经支配的功能眼的剥夺眼支配的外侧膝状体核的板层。急性单眼剥夺在任何膝状体板层的蛋白质合成率没有产生差异变化。
Local rates of cerebral protein synthesis were determined in newborn rhesus monkeys subjected to either acute or chronic monocular visual deprivation. Chronic monocular deprivation resulted in decreased rates of protein synthesis in the laminae of the lateral geniculate nuclei innervated by the deprived eye whereas rates of protein synthesis were normal in geniculate laminae innervated by the functioning eye. Acute monocular deprivation produced no differential changes in rates of protein synthesis in any of the geniculate laminae.