Smart lanthanide coordination polymer fluorescence probe for mercury(II) determination
Smart lanthanide coordination polymer fluorescence probe for mercury(II) determination
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用于汞(II)测定的智能镧系配位聚合物荧光探针
DOI：
10.1016/j.aca.2016.01.044
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发表时间：
2016-03-17
影响因子：
6.2
通讯作者：
Xu, Maotian
中科院分区：
文献类型：
--
作者：
Liu, Baoxia;Huang, Yankai;Xu, Maotian
镧系配位聚合物（LCP）由于其灵活的组成，高度可剪裁的性能和独特的发光特性，最近成为有吸引力的生物传感器材料。本工作以稀土离子为金属结点，环丙沙星为配体分子，AMP为桥接连接基和识别单元，设计了一种用于Hg ~（2+）检测的Tb-CIP/AMP {（CIP，ciprofloxacin）（AMP，adenosine monophosphate）}智能液晶探针。Tb-CIP/AMP由于AMP的引入，使配合物中的水分子被抽走，从而屏蔽了Tb 3+对水分子中O-H振动的猝灭作用，从而发出强烈的绿色发光。在Tb-CIP/AMP体系中加入Hg ~（2+）后，由于AMP与Hg ~（2+）之间的特异性配位作用，使Tb-CIP/AMP体系的荧光发生强烈的猝灭。作为一种汞离子纳米传感器，该探针对汞离子具有良好的选择性和较高的灵敏度，检测限为0.16 nM。该探针具有毫秒级的荧光寿命，用于饮用水和尿样中Hg ~（2+）的检测，结果满意。我们设想，我们的策略，在未来，可以扩展到指定的其他基于LCP的超敏时间门控发光检测在生物介质和生物医学成像。(C)2016爱思唯尔B. V.保留所有权利。
Lanthanide coordination polymers (LCPs) have recently emerged as attractive biosensor materials due to their flexible components, high tailorable properties and unique luminescence features. In this work, we designed a smart LCP probe of Tb-CIP/AMP {(CIP, ciprofloxacin) (AMP, adenosine monophosphate)} for Hg2+ detection by using lanthanide ions as metal nodes, CIP as ligand molecule, and AMP as bridging linker and recognition unit. Tb-CIP/AMP emits strong green luminescence due to the inclusion of AMP, which withdraws the coordinated water molecules and shields Tb3+ from the quenching effect of O-H vibration in water molecules. The subsequent addition of Hg2+ into Tb-CIP/AMP can strongly quench the fluorescence because of the specific coordination interaction between AMP and Hg2+. As a kind of Hg2+ nanosensor, the probe exhibited excellent selectivity for Hg2+ and high sensitivity with detection limit of 0.16 nM. In addition, the probe has long fluorescence lifetime up to millisecond and has been applied to detect Hg2+ in drinking water and human urine samples with satisfactory results. We envision that our strategy, in the future, could be extended to the designation of other LCP-based hypersensitive time-gated luminescence assays in biological media and biomedical imaging. (C) 2016 Elsevier B.V. All rights reserved.