Association between ulcerative colitis and multiple sclerosis
Association between ulcerative colitis and multiple sclerosis
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溃疡性结肠炎与多发性硬化症之间的关联
DOI：
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发表时间：
2007
期刊：
影响因子：
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通讯作者：
M. J. Pokorny
中科院分区：
文献类型：
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作者：
C. Pokorny;R. Beran;M. J. Pokorny
炎症性肠病（IBD）和多发性硬化症（MS）之间的关联已经被描述。目前的研究是为了进一步探讨这种联系。回顾了IBD和MS患者的个人记录。此外，还对悉尼一家大型三级教学医院1996-2006年的医疗记录进行了检索。4例患者（3女1男）同时患有溃疡性结肠炎和多发性硬化症。我们的克罗恩病患者中没有发生多发性硬化症。溃疡性结肠炎和多发性硬化症之间的联系似乎是真实存在的，可能有助于确定导致这两种疾病的共同因素。在这项研究中没有发现多发性硬化症和克罗恩病之间的联系，这引发了人们对为什么会出现这种差异的思考。随着IBD生物疗法的使用越来越多，以及它们有引起脱髓鞘的倾向，认识到两者之间的关联变得更加重要。
An association between inflammatory bowel disease (IBD) and multiple sclerosis (MS) has been described. The current study was undertaken to explore this association further. Personal records of patients with IBD and MS were reviewed. In addition, a search of medical records at a large tertiary teaching hospital in Sydney was carried out for the years 1996–2006. Four patients (three women and one man) with both ulcerative colitis and MS were identified. MS did not occur in any of our patients with Crohn’s disease. The association between ulcerative colitis and MS appears to be real and may help identify common factors involved in the cause of these two diseases. No association was found in this study between MS and Crohn’s disease, sparking consideration why such difference should occur. With the increasing use of biological therapies in IBD and their reported propensity to cause demyelination, recognition of an association is all the more important.
影响因子：
158.5
作者：
Sandborn, WJ;Colombel, JF;Rutgeerts, P
通讯作者：
Rutgeerts, P