A case of atypical Takayasu arteritis initially presenting with peripheral artery disease
A case of atypical Takayasu arteritis initially presenting with peripheral artery disease
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以外周动脉疾病为首发症状的非典型大动脉炎一例
DOI：
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发表时间：
2014
期刊：
影响因子：
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通讯作者：
Y. Nishioka
中科院分区：
文献类型：
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作者：
H. Kawano;M. Hanibuchi;Terumi Yoshijima;Yuko Toyoda;J. Kishi;Toshifumi Tezuka;Y. Nishioka
一位28岁女性因高血压性视网膜病变而发生雷诺现象及突发性左视力丧失。一年半后，她注意到右脚周围发冷和麻木。增强计算机断层扫描显示左桡动脉和双侧胫动脉明显狭窄。最初，诊断为特发性外周动脉闭塞性疾病（PAD）。尽管使用抗血小板药物和血管扩张剂，PAD仍逐渐进展，冠状动脉造影显示左冠状动脉瘤。然后，她出现了同样的缺血性症状，即由视神经乳头水肿引起的右手和左侧视力丧失。尽管18 F-氟脱氧葡萄糖正电子发射断层扫描显示无异常，且HLA-B52和HLA-B39均呈阴性，但在排除其他可能疾病的情况下，她被诊断为非典型高安动脉炎（TA）。据我们所知，这是第一例TA合并冠状动脉瘤和PAD。对于TA患者，应考虑到中等大小的血管病变，如外周肢体动脉。
A 28-year-old woman developed Raynaud’s phenomenon and sudden left visual loss due to hypertensive retinopathy. One and a half years later, she noticed peripheral coldness and numbness of right foot. Enhanced computed tomography showed remarkable stenosis of left radial and bilateral tibial arteries. Initially, the diagnosis of idiopathic peripheral arterial occlusive disease (PAD) was made. PAD gradually progressed despite the medication with antiplatelet drug and vasodilator, and coronary angiography revealed a left coronary artery aneurysm. Then, she developed the same ischemic symptom of right hand and left visual loss caused by papilledema. Although 18 F-fluorodeoxyglucose positron-emission tomography showed no abnormalities, and both HLA-B52 and HLA-B39 were negative, she was diagnosed with atypical Takayasu arteritis (TA) by exclusion of other possible diseases. To the best of our knowledge, this is the first case of TA with coronary aneurysm and PAD. In TA patients, the involvement of medium-sized vascular lesion such as peripheral extremity arteries should be considered.
影响因子：
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作者：
Jennette, J. C.;Falk, R. J.;Watts, R. A.
通讯作者：
Watts, R. A.