Oncogenic Drivers and Development.

Oncogenic Drivers and Development.
复制标题

致癌驱动因素和发展。

DOI:
10.1158/2159-8290.cd-19-1082
复制
发表时间:
2019
期刊:
影响因子:
28.2
通讯作者:
Cruz Hernandez D
Cruz Hernandez D
中科院分区:
医学1区
文献类型:
--
作者:
Cruz Hernandez D

文献摘要

参考文献

相似文献

摘要在本期《癌症发现》中,Lopez 及其同事表明,由嵌合转录因子 CBFA2T3-GLIS2 引起的侵袭性急性白血病表型随转化细胞的发育阶段(即胎儿与成人)而变化。这可能是儿科癌症的一般原则,并开始解释为什么某些癌症表型在婴儿和幼儿中更常见,而另一些癌症表型在老年人中更常见。请参阅 Lopez 等人的相关文章,第 17 页。 1736.
SummaryIn this issue ofCancer Discovery, Lopez and colleagues show that the aggressive acute leukemic phenotype caused by the chimeric transcription factor CBFA2T3–GLIS2 varies depending on the developmental stage of the cell transformed (i.e., fetal vs. adult). This is likely a general principle in pediatric cancers and begins to explain why some cancer phenotypes are more common in infants and young children, whereas others are more frequent in older individuals.See related article by Lopez et al., p. 1736.
DOI: 10.1182/bloodadvances.2019000554
发表时间: 2019-08
期刊: Blood advances
影响因子: 7.5
作者:
Theresa Okeyo-Owuor;Yanan Li;Riddhi M Patel;Wei Yang;Emily B. Casey;Andrew S. Cluster;Shaina N. Porter;D. Bryder;Jeffrey A. Magee
通讯作者: Theresa Okeyo-Owuor;Yanan Li;Riddhi M Patel;Wei Yang;Emily B. Casey;Andrew S. Cluster;Shaina N. Porter;D. Bryder;Jeffrey A. Magee
DOI: 10.1084/jem.20121343
发表时间: 2012-10-22
期刊: The Journal of experimental medicine
影响因子: --
作者:
Thiollier C;Lopez CK;Gerby B;Ignacimouttou C;Poglio S;Duffourd Y;Guégan J;Rivera-Munoz P;Bluteau O;Mabialah V;Diop M;Wen Q;Petit A;Bauchet AL;Reinhardt D;Bornhauser B;Gautheret D;Lecluse Y;Landman-Parker J;Radford I;Vainchenker W;Dastugue N;de Botton S;Dessen P;Bourquin JP;Crispino JD;Ballerini P;Bernard OA;Pflumio F;Mercher T
通讯作者: Mercher T
DOI: 10.1016/j.stem.2015.05.003
发表时间: 2015-07-02
期刊: Cell stem cell
影响因子: 23.9
作者:
Pietras EM;Reynaud D;Kang YA;Carlin D;Calero-Nieto FJ;Leavitt AD;Stuart JM;Göttgens B;Passegué E
通讯作者: Passegué E