Effect of allopurinol on tissue ATP, ADP and AMP concentrations in renal ischaemia

Effect of allopurinol on tissue ATP, ADP and AMP concentrations in renal ischaemia
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别嘌呤醇对肾缺血组织 ATP、ADP 和 AMP 浓度的影响

DOI:
10.1002/bjs.1800610716
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发表时间:
1974
影响因子:
9.6
通讯作者:
P. Fitzgerald
P. Fitzgerald
中科院分区:
医学1区
文献类型:
--
作者:
S. Cunningham;T. V. Keaveny;P. Fitzgerald

文献摘要

被引文献

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本文研究了别嘌醇对大鼠肾脏缺血及脑缺血恢复过程中A、TP、ADP、AMP含量的影响。在脑缺血和脑缺血后的恢复期,用别嘌醇治疗的动物与对照组动物相比,其体内的ATP、ADP和AMP浓度显著升高。
The effect of allopurinol on the concentrations of A TP, ADP and AMP in rat kidneys during ischaemia and postischaemic recovery was studied. Significantly higher concentrations of ATP, ADP and AMP were maintained in the allopurinol‐treated animals as compared with the control animals during ischaemic and postischaemic recovery.