Cesarean delivery and respiratory distress syndrome: Does labor make a difference?
Cesarean delivery and respiratory distress syndrome: Does labor make a difference?
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DOI：
10.1016/j.ajog.2005.05.038
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发表时间：
2005-09-01
影响因子：
9.8
通讯作者：
Chambliss, LR
中科院分区：
文献类型：
--
作者：
Gerten, KA;Coonrod, DV;Chambliss, LR
目的：本研究的目的是确定剖宫产是否是呼吸窘迫综合征（RDS）的危险因素，如果这种风险是修改前careos.Study设计：这项以人口为基础的病例对照研究比较了4778例RDS的5倍，许多controls.Results：未经调整，剖宫产与RDS，比值比（OR）3.5。(95% CI 3.2-3.8）。在控制了潜在的混杂变量后，剖宫产仍然是一个独立的风险因素，OR 2.3（95%CI 2.1-2.6）。分娩显著改变了这一风险（P = 0.02）-有分娩，剖宫产的OR为1.9（95%CI 2.2-2.9），无分娩，OR为2.6（95%CI 1.3-2.8）。结论：剖宫产是RDS的独立危险因素。剖宫产前分娩的风险降低，但仍然升高。这支持了在剖腹产前确定胎儿肺成熟度的重要性，特别是在临产前进行。(C)2005 Mosby，Inc. All rights reserved.
Objective: The purpose of this study was to determine if cesarean delivery is a risk factor for respiratory distress syndrome (RDS) and if this risk is modified by labor before cesarean.Study design: This population-based case-control study compared 4778 cases of RDS to 5 times as many controls.Results: Unadjusted, cesarean delivery was associated with RDS, odds ratio (OR) 3.5.(95% CI 3.2-3.8). After controlling for potential confounding variables, cesarean remained an independent risk factor, OR 2.3 (95% CI 2.1-2.6). Labor modified this risk significantly (P = .02) - with labor, cesarean delivery had an OR of 1.9 (95% CI 2.2-2.9), without labor, the OR was 2.6 (95% CI 1.3-2.8).Conclusion: Cesarean delivery was an independent risk factor for RDS. The risk was reduced with labor before cesarean, but still elevated. This supports the importance of being certain of fetal lung maturity before cesarean delivery, particularly when done before labor. (C) 2005 Mosby, Inc. All rights reserved.