Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis.
Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis.
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DOI：
10.1016/j.cld.2004.06.008
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发表时间：
2004-11-01
影响因子：
5.1
通讯作者：
Neuschwander-Tetri, Brent A
中科院分区：
文献类型：
--
作者：
Harrison, Stephen A;Neuschwander-Tetri, Brent A
非酒精性脂肪性肝病（NAFLD）是一种公认的慢性肝病形式，影响儿童和成人，受到了越来越多的关注。近期，NAFLD与胰岛素抵抗相关联，其发病率和患病率可能在上升，与美国肥胖和糖尿病的增加情况相似。本文包含了对NAFLD自然病程和发病机制的当前观点，并描述了这种疾病诊断和治疗的当前趋势。
Nonalcoholic fatty liver disease (NAFLD) is a well-recognized form of chronic liver disease affecting both children and adults that has gained increased recognition. Recently NAFLD has been associated with insulin resistance and its incidence and prevalence is likely increasing, paralleling the rise in obesity and diabetes mellitus in the United States. The article includes current thoughts on the natural history and pathogenesis of NAFLD and describes current trends in the diagnosis and treatment of this condition.