The Wisconsin epidemiologic study of diabetic retinopathy. IV. Diabetic macular edema.

The Wisconsin epidemiologic study of diabetic retinopathy. IV. Diabetic macular edema.
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DOI:
10.1016/s0161-6420(84)34102-1
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发表时间:
1984-12
期刊:
影响因子:
13.7
通讯作者:
R. Klein;B. Klein;S. Moss;M. Davis;D. DeMets
R. Klein;B. Klein;S. Moss;M. Davis;D. DeMets
中科院分区:
医学1区
文献类型:
--
作者:
R. Klein;B. Klein;S. Moss;M. Davis;D. DeMets

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在威斯康星州南部的一项以人群为基础的研究中,研究了黄斑水肿的患病率及其与许多危险因素的关系。黄斑水肿是根据立体眼底照片或临床记录和照片中记录的过去病史来确定的。对于诊断为糖尿病的年龄小于30岁且正在服用胰岛素的参与者(n = 919),黄斑水肿的患病率从糖尿病患者少于5年的0%到糖尿病患者病程超过20年的29%不等。在这些人中,黄斑水肿与糖尿病持续时间较长、蛋白尿、利尿剂使用、男性和较高的糖化血红蛋白有关。对于诊断年龄为30岁或以上的患者(n = 1121),黄斑水肿的患病率从糖尿病患者少于5年的3%到糖尿病患者病程超过20年的28%不等。在这些人中,黄斑水肿的存在与糖尿病持续时间较长、收缩压较高、胰岛素使用、糖化血红蛋白较高以及蛋白尿的存在有关。
The prevalence of macular edema and its relationship to a number of risk factors were examined in a population-based study in southern Wisconsin. Macular edema was determined from its presence on stereoscopic fundus photographs or from past history as recorded and documented in clinic records and photographs. For participants whose age at diagnosis of diabetes was less than 30 years and who were taking insulin (n = 919), prevalence rates of macular edema varied from 0% in those who had diabetes less than 5 years to 29% in those whose duration of diabetes was 20 or more years. In these persons, macular edema was associated with longer duration of diabetes, presence of proteinuria, diuretic use, male gender and higher glycosylated hemoglobin. For those whose age at diagnosis was 30 years or older (n = 1121), prevalence rates of macular edema varied from 3% in those who had diabetes less than 5 years to 28% in those whose duration of diabetes was 20 or more years. In these persons, presence of macular edema was associated with longer duration of diabetes, higher systolic blood pressure, insulin use, higher glycosylated hemoglobin, and presence of proteinuria.