Lamellar bone: Structure-function relations
Lamellar bone: Structure-function relations
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DOI：
10.1006/jsbi.1999.4107
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发表时间：
1999-06-30
影响因子：
3
通讯作者：
Wagner, HD
中科院分区：
文献类型：
--
作者：
Weiner, S;Traub, W;Wagner, HD
术语“骨骼”是指具有复杂的分层组织结构的一族材料。这些结构主要适应骨骼所实现的各种机械功能。在这里，我们回顾一种骨结构类型——板层骨的结构-力学关系。这是包括人类在内的许多哺乳动物中最丰富的类型。层状单元由五个子层组成。每个子层都是排列整齐的矿化胶原纤维的阵列。这些阵列的方向在每个子层中相对于胶原原纤维轴和晶体层都不同，从而形成复杂的旋转胶合板状结构。与其他骨类型不同，板层骨的特定功能无法确定。因此，有人提出层状结构是多功能的——骨材料家族的“混凝土”。实验测量的板层骨的机械特性表明，相对于长骨的轴线方向，具有明显的各向异性。将初级骨中形成的层状单元平行阵列与次级形成骨中的圆柱形骨结构的弹性和极限特性进行比较表明，大多数固有机械特性都内置于层状结构中。成骨的主要优点是其断裂特性。基于板层结构并使用混合规则方法对弹性特性进行数学建模可以密切模拟测量的力学特性，从而更深入地了解板层骨的结构-力学关系。 1999 年学术出版社。
The term "bone" refers to a family of materials that have complex hierarchically organized structures. These structures are primarily adapted to the variety of mechanical functions that bone fulfills. Here we review the structure-mechanical relations of one bone structural type, lamellar bone. This is the most abundant type in many mammals, including humans. A lamellar unit is composed of five sublayers. Each sublayer is an array of aligned mineralized collagen fibrils. The orientations of these arrays differ in each sublayer with respect to both collagen fibril axes and crystal layers, such that a complex rotated plywood-like structure is formed. Specific functions for lamellar bone, as opposed to the other bone types, could not be identified. It is therefore proposed that the lamellar structure is multifunctional-the "concrete" of the bone family of materials. Experimentally measured mechanical properties of lamellar bone demonstrate a clear-cut anisotropy with respect to the axis direction of long bones. A comparison of the elastic and ultimate properties of parallel arrays of lamellar units formed in primary bone with cylindrically shaped osteonal structures in secondary formed bone shows that most of the intrinsic mechanical properties are built into the lamellar structure. The major advantages of osteonal bone are its fracture properties. Mathematical modeling of the elastic properties based on the lamellar structure and using a rule-of-mixtures approach can closely simulate the measured mechanical properties, providing greater insight into the structure-mechanical relations of lamellar bone. a 1999 Academic Press.