Severe pneumonia caused by a novel influenza A (H1N1) virus in an asymptomatic emphysematous smoker.
Severe pneumonia caused by a novel influenza A (H1N1) virus in an asymptomatic emphysematous smoker.
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一名无症状肺气肿吸烟者由新型甲型H1N1流感病毒引起的严重肺炎。
DOI：
10.2169/internalmedicine.49.3293
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发表时间：
2010
影响因子：
1.2
通讯作者：
H. Miyachi
中科院分区：
文献类型：
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作者：
H. Ozawa;S. Asai;Guilan Jin;Y. Hasunuma;Chiharu Tanaka;T. Ikeda;Moritsugu Kimura;A. Ueda;T. Yamashita;H. Miyachi
一名49岁女性出现腹泻和高烧，随后出现进行性呼吸困难。在此之前，她一直健康，除了慢性消化不良和腹泻。她有15包年的吸烟习惯。实验室检查显示淋巴细胞减少症、低白蛋白血症和低丙种球蛋白血症。快速流感检测结合RT-PCR检测显示存在新型甲型H1N1流感病毒。胸部计算机断层扫描显示小叶中心型肺气肿。这份报告表明，经常吸烟可能成为一个风险，严重肺炎的患者提出了新的流感A（H1N1）病毒，当伴随无症状肺气肿合并其他问题，如低白蛋白血症和低丙种球蛋白血症。
A 49-year-old female presented with diarrhea and a high fever followed by progressive dyspnea. Until this presentation, she had been healthy except for chronic dyspepsia and diarrhea. She had a smoking habit of 15 pack-years. Laboratory tests revealed lymphopenia, hypoalbuminemia and hypogammaglobulinemia. A rapid influenza test in combination with an RT-PCR assay revealed the presence of the novel influenza A (H1N1) virus. Chest computed tomography revealed centrilobular emphysema. This report suggests that regular smoking may become a risk for severe pneumonia in patients presenting with the novel influenza A (H1N1) virus, when accompanying asymptomatic emphysema is combined with other problems such as hypoalbuminemia and hypogammaglobulinemia.
影响因子：
64.8
作者：
通讯作者：
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2009年创新日本 (2009.9.18)
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影响因子：
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