Gender differences in lateralization of mismatch negativity in dichotic listening tasks
Gender differences in lateralization of mismatch negativity in dichotic listening tasks
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DOI：
10.1016/j.ijpsycho.2008.01.006
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发表时间：
2008-04-01
影响因子：
3
通讯作者：
Kamijima, Kunitoshi
中科院分区：
文献类型：
--
作者：
Ikezawa, Satoru;Nakagome, Kazuyuki;Kamijima, Kunitoshi
目的：为了探讨语言刺激前注意加工功能偏侧化的性别差异，本研究采用双耳分听任务，比较了44名健康志愿者（男23名，女21名）的听觉失匹配负波（MMNs）。MMN产生的纯音和语音刺激进行了比较，检查存在的语言特定的性别差异偏侧化。结果：在语音MMN中，女性EEG的波幅明显大于男性，尤其是右半球，而SCD的结果显示男性仅为左半球优势和对侧优势。纯音MMN，没有显着的性别差异半球偏侧出现在EEG或SCD findings.Conclusion：而男性表现出左侧激活语音MMN，女性表现出更多的双边活动。此外，对侧优势的SCD分布与耳朵接收偏差刺激的男性表明，同侧输入，以及跨胼胝体同侧侧半球转移更受抑制的男性比在females.Significance：本研究的结果表明，功能侧化subserving预先注意检测语音变化的性别之间的差异。这些结果强调了在MMN的研究中考虑性别差异的重要性，特别是当采用语音刺激时。此外，他们支持Voyer和Flight的观点[Voyer，D.，Flight，J.，2001.双耳两分任务偏侧化的性别差异：报告策略的影响。Cortex 37，345-362.]语言功能的半球侧化的性别差异是在良好管理的注意条件下观察到的，这符合MMN测量中采用的条件;受试者被要求将注意力集中到分心任务，从而忽略引起MMN的语音刺激。(C)2008 Elsevier B. V.保留所有权利。
Objective: With the aim of investigating gender differences in the functional lateralization subserving preattentive processing of language stimuli, we compared auditory mismatch negativities (MMNs) using dichotic listening tasks.Methods: Forty-four healthy volunteers, including 23 males and 21 females, participated in the study. MMNs generated by pure-tone and phonetic stimuli were compared, to check for the existence of language-specific gender differences in lateralization. Both EEG amplitude and scalp current density (SCID) data were analyzed.Results: With phonetic MMNs, EEG findings revealed significantly larger amplitude in females than males, especially in the right hemisphere, while SCD findings revealed left hemisphere dominance and contralateral dominance in males alone. With pure-tone MMNs, no significant gender differences in hemispheric lateralization appeared in either EEG or SCD findings.Conclusion: While males exhibited left-lateralized activation with phonetic MMNs, females exhibited more bilateral activity. Further, the contralateral dominance of the SCD distribution associated with the ear receiving deviant stimuli in males indicated that ipsilateral input as well as interhemispheric transfer across the corpus callosum to the ipsilateral side was more suppressed in males than in females.Significance: The findings of the present study suggest that functional lateralization subserving preattentive detection of phonetic change differs between the genders. These results underscore the significance of considering the gender differences in the study of MMN, especially when phonetic stimulus is adopted. Moreover, they support the view of Voyer and Flight [Voyer, D., Flight, J., 2001. Gender differences in laterality on a dichotic task: the influence of report strategies. Cortex 37, 345-362.] in that the gender difference in hemispheric lateralization of language function is observed in a well-managed-attention condition, which fits the condition adopted in the MMN measurement; subjects are required to focus attention to a distraction task and thereby ignore the phonetic stimuli that elicit MMN. (C) 2008 Elsevier B.V. All rights reserved.