Age trends of sibling resemblance for height, weight and BMI during growth in a mixed longitudinal sample from Sarsuna-Barisha, India
Age trends of sibling resemblance for height, weight and BMI during growth in a mixed longitudinal sample from Sarsuna-Barisha, India
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DOI：
10.1080/03014460500087857
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发表时间：
2005-05-01
影响因子：
1.7
通讯作者：
Dasgupta, P
中科院分区：
文献类型：
--
作者：
Rebato, E;Salces, I;Dasgupta, P
背景：尽管一些研究认为兄弟姐妹的相似性在整个生命周期中保持不变，但一些研究强调年龄及其与遗传和环境因素的相互作用在决定某些身体特征的兄弟姐妹相似性方面的重要性。事实上，研究家族相似性的年龄变化对于分析生长过程中观察到的某些变异来源是非常重要的。目的：该研究在西孟加拉邦2-19岁的混合纵向样本中检查了兄弟姐妹在身高、体重和体重指数（BMI）方面的相似性，以分析这些表型在生长过程中兄弟姐妹相似性随年龄的变化。样本和方法：对来自印度南加尔各答半城市地区138个中产阶级核心家庭的245个兄弟和213个姐妹进行了分析。兄弟姐妹相似性的分析是通过最大似然法估计的相关性来进行的。通过对观察到的相关性拟合三次非线性回归，检验了兄弟姐妹相似性随年龄变化的不同趋势模式。结果：结果显示，兄弟姐妹在身高和体重方面的相似性随着年龄的变化而明显变化，尽管BMI的变化程度较小。总的来说，我们发现在婴儿期的相关性值最高，在青春期显著下降，在生长周期结束时呈上升趋势。结论：研究证实了年龄对样本中兄弟姐妹之间身高、体重和身体质量指数相似程度的影响。青春期相关性的急剧下降可以用达到青春期生长突增年龄的个体差异来解释。
Background: Even though some studies have considered that sibling resemblance remains constant throughout the life cycle, several investigations emphasize the importance of age and its interactions with genetic and environmental factors in determining sibling similarity in several bodily traits. In fact, the study of age changes in familial resemblance is of great importance for the analysis of certain sources of variation observed in growth processes.Aim: The study examined sibling resemblance for height, weight and body mass index (BMI) in a mixed longitudinal sample from West Bengal, ages 2-19 years, in order to analyse the variations with age of the sibling resemblance for these phenotypes during growth.Sample and methods: Two hundred and forty-five brothers and 213 sisters from 138 middle-class nuclear families living in a semi-urban area of South Kolkata, India were analysed. The analysis of sibling resemblance was performed through correlations estimated by the maximum-likelihood method. The patterns of different trends of sibling resemblance with age were examined by fitting a cubic non-linear regression to the observed correlations.Results: The results show clear variations with age in the sibling resemblance for the traits height and weight, though to a lesser extent for BMI. In general, we found the highest correlation values during the period of infancy, a remarkable decrease during puberty, and a trend of increase towards the end of the growth cycle.Conclusion: The study confirms the effect of age on the degree of similarity among siblings for height, weight and BMI in the sample. The sharp decline of correlation at adolescence can be interpreted in terms of the individual variation in age of reaching the adolescent growth spurt.