Can the genomics of ecological speciation be predicted across the divergence continuum from host races to species? A case study in Rhagoletis

Can the genomics of ecological speciation be predicted across the divergence continuum from host races to species? A case study in Rhagoletis
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生态物种形成的基因组学可以在从宿主种族到物种的分化连续体中进行预测吗?

DOI:
10.1098/rstb.2019.0534
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发表时间:
2020
期刊:
Philosophical Transactions of the Royal Society B: Biological Sciences
影响因子:
--
通讯作者:
Feder, Jeffrey L.
Feder, Jeffrey L.
中科院分区:
--
文献类型:
--
作者:
Meyers, Peter J.;Doellman, Meredith M.;Ragland, Gregory J.;Hood, Glen R.;Egan, Scott P.;Powell, Thomas H.;Nosil, Patrik;Feder, Jeffrey L.

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评估进化的可预测性的研究通常集中在种群内的短期适应或谱系之间变化的可重复性上。物种形成研究中一个缺失的考虑因素是确定自然选择是否可预测地将种群内的遗传变异转化为物种之间的差异。在这里,我们测试是否以及如何主机相关的选择滞育的时间与全基因组分化在生态物种形成比较祖先山楂和新形成的苹果感染的主机种族Rhagoletis pomonella他们的兄弟物种Rhagoletis mendax攻击蓝莓。山楂品种滞育全基因组关联研究(GWAS)中的57 857个单核苷酸多态性的关联强烈预测了美国密歇根州芬维尔一个实地调查点的三个果蝇种群之间基因组分歧的方向和幅度。苹果族和R. mendax显示,与苹果和蓝莓的结果期比山楂早相关的三条染色体上的假定倒位频率发生了平行变化。在R. mendax揭示了整个基因组的补偿性变化,解释了蓝莓的早期羽化,而不是苹果蝇。因此,一定程度的可预测性,虽然不完全,存在于滞育的基因组学在整个生态形态连续inRhagoletis。这一结果的一般性是放置在其他类似systems.This文章的主题问题的一部分“走向物种形成的完成:生殖隔离超越第一障碍的演变”。
Studies assessing the predictability of evolution typically focus on short-term adaptation within populations or the repeatability of change among lineages. A missing consideration in speciation research is to determine whether natural selection predictably transforms standing genetic variation within populations into differences between species. Here, we test whether and how host-related selection on diapause timing associates with genome-wide differentiation during ecological speciation by comparing ancestral hawthorn and newly formed apple-infesting host races ofRhagoletis pomonellato their sibling speciesRhagoletis mendaxthat attacks blueberries. The associations of 57 857 single nucleotide polymorphisms in a diapause genome-wide-association study (GWAS) on the hawthorn race strongly predicted the direction and magnitude of genomic divergence among the three fly populations at a field site in Fennville, MI, USA. The apple race andR. mendaxshow parallel changes in the frequencies of putative inversions on three chromosomes associated with the earlier fruiting times of apples and blueberries compared to hawthorns. A diapause GWAS onR. mendaxrevealed compensatory changes throughout the genome accounting for the earlier eclosion of blueberry, but not apple flies. Thus, a degree of predictability, although not complete, exists in the genomics of diapause across the ecological speciation continuum inRhagoletis. The generality of this result is placed in the context of other similar systems.This article is part of the theme issue ‘Towards the completion of speciation: the evolution of reproductive isolation beyond the first barriers'.
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