Neurotuberculosis: Control of Steroid-Refractory Paradoxical Inflammatory Reaction With Ruxolitinib.

Neurotuberculosis: Control of Steroid-Refractory Paradoxical Inflammatory Reaction With Ruxolitinib.
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神经结核:用鲁索替尼控制类固醇难治性矛盾炎症反应。

DOI:
10.1093/ofid/ofz422
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发表时间:
2019
影响因子:
4.2
通讯作者:
Holland,StevenM
Holland,StevenM
中科院分区:
医学3区
文献类型:
--
作者:
Xie,YingdaL;Ita-Nagy,Fanny;Chen,RayY;Manion,MauraM;Sereti,Irini;Pei,Luxin;Holland,StevenM

文献摘要

相似文献

与神经结核治疗相关的矛盾炎症反应可导致严重的发病率和死亡率,并且可能无法仅通过类固醇来控制。我们报告使用 Janus 激酶抑制剂鲁索替尼治疗类固醇难治性神经结核矛盾反应。
Paradoxical inflammatory reactions associated with treatment of neurotuberculosis can lead to severe morbidity and mortality and may not be controlled by steroids alone. We report the use of the Janus kinase inhibitor ruxolitinib to treat a steroid-refractory neurotuberculosis paradoxical reaction.