Substantial expression of novel small open reading frames in Oryza sativa

Substantial expression of novel small open reading frames in Oryza sativa
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DOI:
10.4161/psb.27848
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发表时间:
2014-02
影响因子:
2.9
通讯作者:
Masanori Okamoto;Mieko Higuchi-Takeuchi;Minami Shimizu;K. Shinozaki;Kousuke Hanada
Masanori Okamoto;Mieko Higuchi-Takeuchi;Minami Shimizu;K. Shinozaki;Kousuke Hanada
中科院分区:
生物学4区
文献类型:
--
作者:
Masanori Okamoto;Mieko Higuchi-Takeuchi;Minami Shimizu;K. Shinozaki;Kousuke Hanada

文献摘要

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在我们前期结合信息学和分子生物学分析的综合研究中,我们揭示了拟南芥小开放阅读框架(sORF)在形态建成中的生物学功能。在这里,我们报告的序列同源拟南芥sORF丰富的水稻基因组的基因间区域。这些序列代表非蛋白质编码DNA的子集,并且一些被转录成mRNA。这些结果表明,许多与形态建成相关的sORF隐藏在作物物种的基因组中。
In our previous integrated study combining informatics and molecular biology analyses, we revealed that Arabidopsis small open reading frames (sORFs) predicted by computational analysis have biological functions in morphogenesis. Here, we report that sequences homologous to Arabidopsis sORFs are abundant in intergenic regions of the rice genome. These sequences represent a subset of non-protein-coding DNA, and some are transcribed into mRNA. These results indicate that many sORFs associated with morphogenesis are hidden in the genomes of crop species.