Pesticide residues in human breast milk: Risk assessment for infants from Punjab, India

Pesticide residues in human breast milk: Risk assessment for infants from Punjab, India
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DOI:
10.1016/j.scitotenv.2013.06.066
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发表时间:
2013-10-01
影响因子:
9.8
通讯作者:
Pooni, P. A.
Pooni, P. A.
中科院分区:
环境科学与生态学1区
文献类型:
--
作者:
Bedi, J. S.;Gill, J. P. S.;Pooni, P. A.

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印度的旁遮普邦是一个农业社会,农业是农业社会的生命线。为了满足日益增长的人口对食物的需求,滥用农药导致了该地区环境和食品的污染,对母乳样本(n = 53)进行的农药残留分析显示,存在β-、γ-HCH、p,p' DDD、p,p' DDE、p,p' DDT和异狄氏剂,平均浓度分别为97.9、101.7、101.7、101.7、101.7和101.7。239.8、1574.1、1003和90.7 ng g(-1)脂质重量,分别此外,在印度旁遮普的母乳中,还首次报告了本研究中发现的乙型硫丹、硫丹硫酸盐、氯氰菊酯和毒死蜱。随着胎次的增加,母乳中六六六和滴滴涕的残留量呈下降趋势。尽管母乳样本中的六氯环己烷和滴滴涕残留量已大幅下降,但估计的滴滴涕每日摄入量值仍高于粮农组织/世卫组织规定的少数婴儿每日允许摄入量值。(C)2013爱思唯尔有限公司版权所有。
Punjab state in India is an agrarian society, where agriculture is the lifeline of farming community. To keep pace with increasing demands of food for growing population the indiscriminate use of pesticides has led to the contamination of environment and food commodities in this region.Analysis of human breast milk samples (n = 53) for pesticide residues revealed the presence of beta-, gamma-HCH, p,p' DDD, p,p' DDE, p,p' DDT and endrin with mean concentration of 97.9, 101.7, 239.8, 1574.1, 1003 and 90.7 ng g(-1) lipid wt., respectively. In addition, occurrence of beta-endosulfan, endosulfan sulphate, cypermethrin and chlorpyrifos in this study have also been reported for the first time in human breast milk in Punjab, India. With increase in parity, HCH and DDT residue burden in donor's milk decreased. Although levels of HCH and DDT residues in breast milk samples have decreased significantly, yet estimated daily intake values for DDT are higher than the FAO/WHO permissible tolerable daily intake values for few infants. (C) 2013 Elsevier B.V. All rights reserved.