Myocardial conducting system dysfunctions from thoracic impact.
Myocardial conducting system dysfunctions from thoracic impact.
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胸部冲击导致心肌传导系统功能障碍。
DOI：
10.1097/00005373-197806000-00010
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发表时间：
1978
期刊：
影响因子：
--
通讯作者：
C. G. Artinian
中科院分区：
文献类型：
--
作者：
D. Viano;C. G. Artinian
对12只麻醉猪进行钝性胸部撞击后获得的心电图（ECG导联II）的分析表明，所有动物的心脏传导系统都出现了一定程度的创伤：窦房结紊乱、房室交界功能障碍、心室内传导缺陷（例如，束分支阻滞）或心室纤维性颤动。在本研究中，诱导的室颤迅速发展至4只动物死亡。室颤的发生率与测量的生物力学响应参数的比较表明，心室功能障碍与高水平的胸骨加速度（930 g）和冲击速度（10.7 m/s）的显着相关性。室颤的发生与典型的生物力学胸部损伤“指标”无关（即，标准化胸部偏转水平、累积AIS、峰值脊柱加速度或施加的力）。损伤严重程度分级（MCD）随后被开发用于评估心肌传导系统功能障碍。
An analysis of electrocardiograms (ECG lead II) obtained following blunt thoracic impacts conducted on 12 anesthetized pigs indicated that all animals developed some degree of trauma to the heart conducting system: sino-atrial nodal disturbances, atrio-ventricular junctional dysfunction, intraventricular conduction defects (e.g., bundle branch blocks), or ventricular fibrillation. The induced ventricular fibrillation proceeded rapidly to the demise of four animals in this study. A comparison of the occurrence of ventricular fibrillation with measured biomechanical response parameters indicated a significant correlation of ventricular dysfunction with high levels of sternal acceleration (930 g) and impact velocity (10.7 m/s). The initiation of ventricular fibrillation did not correlate with typical biomechanical thoracic injury "indicators" (i.i., level of normalized thoracic deflection, cumulative AIS, peak spinal acceleration, or applied force). An injury severity classification (MCD) was subsequently developed for the evaluation of myocardial conducting system dysfunctions.