DNA-bridged bioconjugation of fluorescent quantum dots for highly sensitive microfluidic protein chips
DNA-bridged bioconjugation of fluorescent quantum dots for highly sensitive microfluidic protein chips
复制标题
用于高灵敏度微流控蛋白质芯片的荧光量子点的 DNA 桥生物共轭
DOI：
10.1039/c0cc01608j
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发表时间：
2010-01-01
影响因子：
4.9
通讯作者：
Fan, Chunhai
中科院分区：
文献类型：
--
作者：
Hu, Mei;He, Yao;Fan, Chunhai
DNA桥接策略用于将链霉亲和素（STV）与发光半导体量子点（QD）容易地缀合，这导致方便且稳定的QD-DNA-生物素-STV缀合物，其用作荧光纳米探针，用于用微流体蛋白质芯片超灵敏地检测癌症生物标志物。
A DNA-bridged strategy is used to facilely conjugate streptavidin (STV) to luminescent semiconductor quantum dots (QDs), which leads to convenient and stable QD-DNA-biotin-STV conjugates that serve as fluorescent nanoprobes for ultrasensitive detection of cancer biomarkers with a microfluidic protein chip.