Intrapartum chlorhexidine vaginal irrigation and chorioamnion and placental microbial colonization.
Intrapartum chlorhexidine vaginal irrigation and chorioamnion and placental microbial colonization.
复制标题
产时氯己定阴道冲洗和绒毛膜羊膜和胎盘微生物定植。
DOI：
10.1016/s0020-7292(03)00272-8
复制
发表时间：
2003
期刊：
影响因子：
--
通讯作者：
Hauth,JC
中科院分区：
文献类型：
--
作者：
Rouse,DJ;Lincoln,T;Cliver,S;Lyon,MD;Andrews,WW;Hauth,JC
Objectives:To determine whether intrapartum chlorhexidine vaginal irrigation reduces microbial colonization of the chorioamnion or placenta.Methods:Secondary analysis was made of a randomized trial. Cultures for aerobic and anaerobic bacteria,Mycoplasmaspecies andUreaplasma urealyticumwere performed using standard isolation techniques.Results:The placentas of 83 trial participants allocated to chlorhexidine and 93 allocated to placebo underwent evaluation. These two groups were statistically balanced for risk factors for infection. Aerobic bacteria were isolated from 47% of the chlorhexidine placentas vs. 51% of the placebo placentas (relative risk 0.9, 95% confidence interval 0.7–1.3), anaerobic bacteria from 30% and 35%, respectively (0.8, 0.5–1.3), group B streptococcus from 12% and 15% (0.8, 0.4–1.7),U. urealyticumfrom 18% and 29% (0.6, 0.4–1.1),Mycoplasmaspecies from 6% and 11% (0.6, 0.2–1.6), and any organism from 57% and 67%, respectively (0.8, 0.7–1.1).Conclusions:Intrapartum chlorhexidine vaginal irrigation was associated with non‐significant reductions in the rates of placental microbial isolation.
