The early influence of COVID-19 pandemic-associated restrictions on pain, mood, and everyday life of patients with painful polyneuropathy.
The early influence of COVID-19 pandemic-associated restrictions on pain, mood, and everyday life of patients with painful polyneuropathy.
复制标题
与 COVID-19 大流行相关的限制对疼痛性多发性神经病患者的疼痛、情绪和日常生活的早期影响。
DOI：
10.1097/pr9.0000000000000858
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发表时间：
2020-11
期刊：
影响因子：
4.8
通讯作者：
Gierthmühlen J
中科院分区：
文献类型：
--
作者：
Kersebaum D;Fabig SC;Sendel M;Sachau J;Lassen J;Rehm S;Hüllemann P;Baron R;Gierthmühlen J
补充数字内容在文本中可用。经验证的问卷调查显示，慢性疼痛性多发性神经病患者的注意力从慢性疼痛转向了COVID-19大流行。SARS-Cov-2大流行需要特别关注其心理影响和对慢性疼痛患者的影响。本研究旨在研究德国政府发起的COVID-19流行相关法规对疼痛性多发性神经病患者的疼痛强度和特征、情绪健康和日常生活的影响。43名患者（在大流行前通过问卷进行了良好评估，并且他们的健康状况在基线和当前评估之间没有变化）在法规生效后2周接受了经过验证的自我报告问卷和COVID-19特定项目的调查。疼痛强度与神经病理性疼痛症状量表总分一样保持稳定甚至改善（t0：33.54 ± 20.48 vs t1：27.38 ± 16.16，P = 0.008）。只有11.6%的人报告了与流行病相关的疼痛恶化。疼痛灾难化量表的反刍评分在t1期间低于大流行管制前（t0：7.81 ± 4.70，t1：6.49 ± 4.39; P = 0.030）。有趣的是，社交生活改变的患者在过去7天的疼痛评分高于没有改变的患者（-1.63 ± 1.60 vs 0.31 ± 1.83; P = 0.01）。生活质量下降，无助感增加，在那些更高的疼痛评级。结果表明，人们的注意力从慢性疼痛状况转向了迫在眉睫的全球大流行威胁。由于这一流行病的影响是持续的和不断变化的，在未来几周内制定衡量参数将是非常令人感兴趣的。
Supplemental Digital Content is Available in the Text. Validated questionnaires revealed a shift of attention from chronic pain towards the COVID-19 pandemic in patients with chronic painful polyneuropathy. The SARS-Cov-2 pandemic requires special attention on its psychological effects and the impact on patients with chronic pain. This study aimed at examining the influence of the COVID-19 pandemic-associated regulations initiated by the German government on pain intensity and characteristics, emotional well-being, and everyday life of patients with painful polyneuropathy. Forty-three patients (well assessed with questionnaires before the pandemic and without change of their health status between baseline and current assessment) were investigated with validated, self-reported questionnaires and COVID-19-specific items 2 weeks after the regulations came into effect. Pain intensity remained stable or even improved like the neuropathic pain symptom inventory total score (t0: 33.54 ± 20.48 vs t1: 27.38 ± 16.16, P = 0.008). Only 11.6% reported a pandemic-associated pain worsening. Rumination scores of the Pain Catastrophizing Scale were lower during t1 compared to before the pandemic regulations (t0: 7.81 ± 4.70, t1: 6.49 ± 4.39; P = 0.030). Interestingly, pain ratings for the last 7 days were higher in patients with a changed social life compared to those without (−1.63 ± 1.60 vs 0.31 ± 1.83; P = 0.01). Quality of life was decreased and helplessness increased in those with higher pain ratings. Results suggest a shift of attention from the chronic pain condition towards the imminent threat of a global pandemic. As the impacts of the pandemic are persistent and evolving, the development of the measured parameters in the forthcoming weeks will be of great interest.