Accuracy of pulse oximetry readings in an animal model of low perfusion caused by emerging pneumonia and sepsis
Accuracy of pulse oximetry readings in an animal model of low perfusion caused by emerging pneumonia and sepsis
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DOI：
10.1007/s00134-003-2116-1
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发表时间：
2004-04-01
影响因子：
38.9
通讯作者：
Franz, AR
中科院分区：
文献类型：
--
作者：
Hummler, HD;Engelmann, A;Franz, AR
目标。为了测试新发脓毒血症引起的低灌注对两种新型脉搏血氧仪性能的影响：Masimo SET与Nellcor Oxismart XL。设计。随机分配两个脉搏血氧仪到两个传感器位置的队列研究。设置。大学动物研究机构。科目。25只成年，麻醉，通气的兔子。干预措施。气管内滴注大肠杆菌诱导肺炎/败血症。测量和结果。采用脉搏血氧仪（SpO(2)）测定血氧饱和度，并连续记录至死亡。动脉血氧饱和度（SaO(2)）每小时用CO血氧仪测量一次，当两个装置之间出现>.5 %的差异时测量一次。SpO(2)传感器安装在两只前腿上，每小时切换一次。总的信号消失时间没有差异[中位3.8分钟（范围0.4-66.6分钟）vs 3.3分钟（范围0-94.5分钟），Masimo SET vs Oxismart XL]。使用Masimo SET和Oxismart XL进行CO氧饱和度测定时，出现错误SpO(2)读数[1（范围0-7）vs 2（范围0-17）]的发作次数更少；p
Objective. To test the effects of low perfusion caused by emerging sepsis on the performance of two new pulse oximetry techniques: Masimo SET in comparison with Nellcor Oxismart XL. Design. Cohort study with random allocation of two pulse oximetry devices to two sensor sites. Setting. University animal research facility. Subjects. Twenty-five adult, anesthetized, ventilated rabbits. Interventions. Pneumonia/sepsis was induced by tracheal instillation of E. coli. Measurements and results. Oxygen saturation was measured by pulse oximetry (SpO(2)) and recorded continuously until death. Arterial oxygen saturation (SaO(2)) was measured hourly by CO oximetry and whenever a difference of >5% between the devices occurred. SpO(2) sensors were positioned at both forelegs and switched hourly. There was no difference in total signal dropout time [median 3.8 min (range 0.4-66.6 min) vs 3.3 min (range 0-94.5 min), Masimo SET vs Oxismart XL]. There were fewer episodes with a false SpO(2) reading [1 (range 0-7) vs 2 (range 0-17)] using the Masimo SET vs the Oxismart XL as verified by CO oximetry; p