Collagen production and types in fibrous capsules around breast implants.
Collagen production and types in fibrous capsules around breast implants.
复制标题
乳房植入物周围纤维胶囊中胶原蛋白的产生和类型。
DOI：
10.1097/00006534-198406000-00012
复制
发表时间：
1984
影响因子：
3.6
通讯作者：
I. Cohen
中科院分区：
文献类型：
--
作者：
B. McCoy;P. Person;I. Cohen
这项研究表明，胶原蛋白生成增加但 III 型：I 型胶原蛋白比例改变与乳腺包膜挛缩相关。因此，从这些发现和之前的数据来看，包膜挛缩似乎与生物化学和组织学上异物反应的增加有关。需要进一步的研究来直接评估某些植入物周围收缩的原因，而另一些则不然；然而，似乎可以通过控制与收缩相关的生化以及细胞事件来控制包膜挛缩。此类研究仍有待完成。
This study demonstrates that increased collagen production but not an altered ratio of type III:I collagen is associated with breast capsular contracture. From these findings and previous data, therefore, it appears that capsular contracture is associated with increased foreign-body response biochemically as well as histologically. Further studies are required to directly assess the reasons for contraction around some implants and not others; however, it appears that control of capsular contracture may be achieved by controlling biochemical as well as cellular events associated with contraction. Such studies remain to be done.