The value of narrow band imaging combined with stroboscopy for the detection of applanate indiscernible early-stage vocal cord cancer
The value of narrow band imaging combined with stroboscopy for the detection of applanate indiscernible early-stage vocal cord cancer
复制标题
窄带成像联合频闪检查对扁平不可分辨早期声带癌的检出价值
DOI：
10.1080/00016489.2017.1388542
复制
发表时间：
2018-01-01
影响因子：
1.4
通讯作者：
Hou, Lizhen
中科院分区：
文献类型：
--
作者：
Yang, Yifan;Fang, Jugao;Hou, Lizhen
摘要背景：窄带成像（NBI）和频闪镜是检测声带恶性病变的非侵入性技术。本研究旨在探讨联合内镜检查对临床难以鉴别的早期声带癌的诊断价值。方法：回顾性分析110例160个可疑声带恶性病变的临床资料。所有患者在NBI后立即进行频闪镜检查，并进行白色光内镜检查（WLE）。行切除活检，进行组织病理学检查。结果如下：NBI和WLE联合频闪镜检查组的诊断特异性和PPV均高于NBI和WLE未联合频闪镜检查组（88.9%vs72.5%，88.4%vs60.9%）。然而，两组的诊断敏感性无显著差异（69.3% vs 67.7%）。结论：NBI和WLE联合频闪镜检查具有临床可行性和诊断特异性的优点，是一种很有前途的早期声带癌诊断方法。
Abstract Background: Narrow band imaging (NBI) and stroboscopy are non-invasive techniques to detect the malignant lesions of the vocal cord. This study was to assess the diagnostic value of combined endoscopic analysis in the applanate indiscernible early-stage vocal cord cancer. Methods: A total of 110 patients with 160 suspicious vocal cord malignant lesions were included in this retrospective study. Stroboscopy was immediately performed after NBI and white light endoscopy (WLE) were performed in all patients. Excisional biopsy was performed to examine histopathology examination. Results: We found that the diagnostic specificity and PPV were higher in the NBI and WLE combined with stroboscopy group than in the NBI and WLE group without stroboscopy (88.9% vs 72.5%, 88.4% vs 60.9%). However, the diagnostic sensitivity was not significantly different in those two groups (69.3% vs 67.7%). Conclusion: NBI and WLE combined with stroboscopy is a promising method to detect early-stage vocal cord cancer with the advantage of clinical feasibility and diagnostic specificity.