Variation among pathologists in histologic grading of canine cutaneous mast cell tumors
Variation among pathologists in histologic grading of canine cutaneous mast cell tumors
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DOI：
10.1177/104063870501700305
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发表时间：
2005-05-01
影响因子：
1.5
通讯作者：
Howerth, EW
中科院分区：
文献类型：
--
作者：
Northrup, NC;Harmon, BG;Howerth, EW
来自一家兽医机构的10名兽医病理学家对相同的60只犬皮肤肥大细胞瘤(MCT)进行了独立的组织学分级。不同病理学家对MCT的分级有显著差异(P<；0.001)。对于这项研究中的病理学家来说，被指定为低级别的可能性显著更高，他们使用发表的犬皮MCT组织学分级的参考文献，允许将皮下MCT或有核分裂图形的MCT归入低级别类别(分别为P<；0.0001和P<；0.0001)。
Ten veterinary pathologists at 1 veterinary institution independently assigned histologic grades to the same 60 canine cutaneous mast cell tumors (MCTs). There was significant variation among pathologists in grading the MCTs (P < 0.001). The probability of assigning a low grade was significantly higher for the pathologists in this study who use a published reference for histologic grading of canine cutaneous MCTs that allows subcutaneous MCTs or MCTs with mitotic figures to be included in the low-grade category (P < 0.0001 and P < 0.0001, respectively).