Neurogenesis in the neocortex of adult primates

Neurogenesis in the neocortex of adult primates
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DOI:
10.1126/science.286.5439.548
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发表时间:
1999-10-15
期刊:
影响因子:
56.9
通讯作者:
Gross, CG
Gross, CG
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Gould, E;Reeves, AJ;Gross, CG

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在灵长类动物中,前额叶、下颞叶和后顶叶皮层对认知功能很重要。结果表明,在成年猕猴中,新的神经元被添加到这三个新皮质关联区,但不是一个主要的感觉区(纹状体皮质)。新生神经元起源于室管膜下区,并通过白色物质迁移到新皮质,在那里它们延伸轴突。这些新生神经元在成年期不断增加,可能在联合新皮质的功能中发挥作用。
In primates, prefrontal, inferior temporal, and posterior parietal cortex are important for cognitive function. It is shown that in adult macaques, new neurons are added to these three neocortical association areas, but not to a primary sensory area (striate cortex). The new neurons appeared to originate in the subventricular zone and to migrate through the white matter to the neocortex, where they extended axons, These new neurons, which are continually added in adulthood, may play a role in the functions of association neocortex.