Disrupted timing of discontinuous but not continuous movements by cerebellar lesions
Disrupted timing of discontinuous but not continuous movements by cerebellar lesions
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DOI：
10.1126/science.1083661
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发表时间：
2003-05-30
期刊：
影响因子：
56.9
通讯作者：
Ivry, RB
中科院分区：
文献类型：
--
作者：
Spencer, RMC;Zelaznik, HN;Ivry, RB
小脑损伤患者在运动的时间控制方面表现出缺陷。我们报告这些缺陷仅限于不连续的运动。小脑患者在产生连续的、有节奏的运动时，没有表现出时间变异性的缺陷。我们假设连续运动的时间属性是紧急的，反映了与小脑无关的其他控制参数的操作。相反，不连续的运动需要对时间目标的明确表征，这是小脑的功能。对显式时间表征的要求为小脑参与一系列任务提供了一个简洁的解释。
Patients with cerebellar damage are known to exhibit deficits in the temporal control of movements. We report that these deficits are restricted to discontinuous movements. Cerebellar patients exhibited no deficit in temporal variability when producing continuous, rhythmic movements. We hypothesize that the temporal properties of continuous movements are emergent and reflect the operation of other control parameters not associated with the cerebellum. In contrast, discontinuous movements require an explicit representation of the temporal goal, a function of the cerebellum. The requirement for explicit temporal representation provides a parsimonious account of cerebellar involvement in a range of tasks.