Accelerated Development of Colloidal Nanomaterials Enabled by Modular Microfluidic Reactors: Toward Autonomous Robotic Experimentation
Accelerated Development of Colloidal Nanomaterials Enabled by Modular Microfluidic Reactors: Toward Autonomous Robotic Experimentation
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DOI：
10.1002/adma.202004495
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发表时间：
2020-12-02
影响因子：
29.4
通讯作者：
Abolhasani, Milad
中科院分区：
文献类型：
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作者：
Volk, Amanda A.;Epps, Robert W.;Abolhasani, Milad
近年来，微流控技术已成为先进合成和快速优化各种溶液处理纳米材料的强大方法，包括半导体量子点和纳米片，以及金属等离子体和网状框架纳米颗粒。这些流体系统以无与伦比的效率和采样率提供了以前无法实现的测量和合成条件。尽管有这些优点，微流体系统尚未被胶体纳米材料社区广泛采用。为了帮助弥合差距，这份进展报告详细介绍了微流控反应器设计和性能的基本原理，以及在线诊断和自主机器人实验策略的现状，以及各种胶体纳米材料的尺寸，形状和成分控制合成。通过讨论微流控平台在最近高优先级胶体纳米材料研究中的应用及其与快速新兴的基于人工智能的决策策略整合的潜力，本报告旨在鼓励微流控反应器工程师和胶体纳米材料化学家之间的跨学科合作。这两项研究工作的全面融合大大加快和增强了纳米材料的发现，优化和制造。
In recent years, microfluidic technologies have emerged as a powerful approach for the advanced synthesis and rapid optimization of various solution-processed nanomaterials, including semiconductor quantum dots and nanoplatelets, and metal plasmonic and reticular framework nanoparticles. These fluidic systems offer access to previously unattainable measurements and synthesis conditions at unparalleled efficiencies and sampling rates. Despite these advantages, microfluidic systems have yet to be extensively adopted by the colloidal nanomaterial community. To help bridge the gap, this progress report details the basic principles of microfluidic reactor design and performance, as well as the current state of online diagnostics and autonomous robotic experimentation strategies, toward the size, shape, and composition-controlled synthesis of various colloidal nanomaterials. By discussing the application offluidic platforms in recent high-priority colloidal nanomaterial studies and their potential for integration with rapidly emerging artificial intelligence-based decision-making strategies, this report seeks to encourage interdisciplinary collaborations between microfluidic reactor engineers and colloidal nanomaterial chemists. Full convergence of these two research efforts offers significantly expedited and enhanced nanomaterial discovery, optimization, and manufacturing.