Short-Term Psychodynamic Psychotherapy with Mentalization-Based Techniques in Major Depressive Disorder patients: Relationship among alexithymia, reflective functioning, and outcome variables - A Pilot study

Short-Term Psychodynamic Psychotherapy with Mentalization-Based Techniques in Major Depressive Disorder patients: Relationship among alexithymia, reflective functioning, and outcome variables - A Pilot study
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DOI:
10.1111/papt.12110
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发表时间:
2017-09-01
影响因子:
3.4
通讯作者:
Barone, Lavinia
Barone, Lavinia
中科院分区:
医学2区
文献类型:
--
作者:
Bressi, Cinzia;Fronza, Silvia;Barone, Lavinia

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目标在抑郁症患者中,最近的进展凸显了心理化方面的障碍:识别和解释自己或他人的心理状态。短期心理动力学心理治疗(STPP)已被证明可以有效减轻这些受试者的症状并提高关系/功能能力。因此,我们研究的第一个目的是评估 STPP 与基于心理化的技术 (STMBP) 对其临床结果的有效性,第二个目的是调查与抑郁症受试者治疗结果相关的反射功能和述情障碍。设计在 STMBP 治疗之前对反射功能、述情障碍和抑郁症进行基线评估。患者在40周后(T1)和治疗结束时1年后的随访(T2)相继进行重新测试。方法共有24名主要诊断为重度抑郁症(MDD)的患者接受了由两名专家治疗师进行的STMBP。两名临床治疗师在基线 (T0) 收集了整体功能评估 (GAF)、多伦多述情障碍量表 20 (TAS-20) 和汉密尔顿抑郁评定量表 (HAM-D) 数据,以及由两名训练有素的评估员评估的 RF 评分。 HAM-D、TAS-20 和 GAF 随访在治疗结束后 40 周 (T1) 和 1 年随访 (T2) 后进行。结果结果强调我们的样本中 HAM-D 和 TAS-20 评分均有所改善。此外,还发现 RF 和 TAS-20 之间呈负相关。 T0 时的 HAM-D 和 RF 都会影响治疗结束时的抑郁结果。结论结果证实了 STMBP 在 MDD 中的有效性,也表明 RF 与述情障碍之间呈负相关。
ObjectivesIn depressed patients, recent advances have highlighted impairment in mentalizing: identifying and interpreting one's own or other's mental states. Short-Term Psychodynamic Psychotherapy (STPP) has proven to be effective in reducing symptoms and improving relational/functional abilities in these subjects. Therefore, the first aim of our study was to evaluate effectiveness of STPP with Mentalization-Based Techniques (STMBP) on their clinical outcomes and the second, to investigate Reflective Functioning and alexithymia concerning treatment outcomes in depressed subjects.DesignA baseline evaluation of reflective functioning, alexithymia and depression was conducted before an STMBP treatment. Patients were re-tested successively after 40weeks (T1) and in a follow-up after 1year at the end of the treatment (T2).MethodsA total of 24 patients principally diagnosed with Major Depressive Disorder (MDD) underwent a STMBP conducted by two expert therapists. Global Assessment Functioning (GAF), Toronto Alexithymia Scale-20 (TAS-20) and Hamilton Depression Rating Scale (HAM-D) data were collected at the baseline (T0) by two clinical therapists, along with RF scores rated by two trained raters. HAM-D, TAS-20 and GAF follow-ups were conducted at the end of the treatment after 40weeks (T1) and after 1-year follow-up (T2).ResultsResults highlighted an improvement of both HAM-D and TAS-20 scores in our sample. Moreover, a negative correlation between RF and TAS-20 was found. Both HAM-D and RF at T0 influenced depressive outcomes at the end of the treatment.ConclusionsResults confirmed the effectiveness of STMBP in MDD, suggesting also an inverse association between RF and alexithymia.