Beliefs about medicines and adherence among Swedish migraineurs
Beliefs about medicines and adherence among Swedish migraineurs
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DOI：
10.1345/aph.1k354
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发表时间：
2008-01-01
影响因子：
2.9
通讯作者：
Linde, Mattias
中科院分区：
文献类型：
--
作者：
Hedenrud, Tove;Jonsson, Pernilla;Linde, Mattias
背景技术背景：药物治疗依从性低的问题在偏头痛中与在任何其他疾病中一样普遍，对患者具有重要后果，例如生活质量受损和缺勤。对药物的信念已被确定为坚持的最重要因素之一。目的：分析瑞典三级保健诊所偏头痛患者对药物和药物相关因素的信念是否与坚持预防性药物治疗有关。方法：在瑞典的一家三级保健诊所向偏头痛患者发放问卷。所有参与者最近都被开了预防性药物。问卷包括背景问题、关于疾病特征、感知效果和所用偏头痛药物的不良反应的问题、药物信念问卷和药物依从性报告量表。还包括经同意从患者记录中收集的药物相关变量。采用Logistic回归分析分析药物信念、药物相关变量与预防性药物依从性之间的关系。结果：在研究的174名参与者中，64%的人被认为遵守了他们规定的预防性药物。与使用其他药物（例如，三环类抗抑郁药[TCA]或抗癫痫药）的患者相比，使用β受体阻滞剂的患者的依从性明显更高;服用TCA的患者则相反。教育程度最低的受访者（
BACKGROUND: The problem of low adherence to drug therapy is as prevalent in migraine as in any other disorder, with important consequences for the patient, I such as impaired quality of life and absence from work. Beliefs about medicines have been identified as one of the most significant factors for adherence. OBJECTIVE: To analyze whether beliefs about medicines and medication-related factors are associated with adherence to prophylactic drug therapy among migraineurs at a Swedish tertiary care clinic. METHODS: A questionnaire was distributed to migraineurs visiting a tertiary care clinic in Sweden. All participants had recently been prescribed prophylactic medicine. The questionnaire was comprised of background questions, questions about disease characteristics, perceived effects, and adverse effects of migraine medications used, the Beliefs about Medicines questionnaire, and the Medication Adherence Report Scale. Medication-related variables, collected from patients' records with consent, were also included. Logistic regression analysis was performed to analyze the association between beliefs about medicines, medication-related variables, and adherence to prophylactic drugs. RESULTS: Of the 174 participants in the study, 64% were considered to be adherent to their prescribed prophylactic medicine. Users of beta-blockers were significantly more adherent compared with patients using other drugs (eg, tricyclic antidepressants [TCAs] or antiepileptics); the reverse was true for patients taking TCAs. Respondents with the lowest level of education (