Can farm milk consumption prevent allergic diseases?
Can farm milk consumption prevent allergic diseases?
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DOI：
10.1111/j.1365-2222.2010.03665.x
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发表时间：
2011-01-01
影响因子：
6.1
通讯作者：
von Mutius, E.
中科院分区：
文献类型：
--
作者：
Braun-Fahrlaender, C.;von Mutius, E.
牛奶是人类饮食的重要组成部分，也是某些人食物过敏的来源。医学指导强烈反对食用生奶，因为已知的健康风险与未经巴氏消毒的牛奶中存在的致病菌有关。尽管存在这些风险，但越来越多的流行病学证据表明，食用未经加工的牛奶不会增加，反而会降低哮喘，花粉热和特应性过敏的风险。本文回顾了流行病学文献，并讨论了可能负责这种保护的未加工牛奶的成分。它侧重于细菌在原料奶中的作用，脂肪酸分布，乳清蛋白，最后是牛奶中过敏原的作用。尽管流行病学证据一致表明，食用未加工牛奶对哮喘、花粉热和特应性致敏的发展具有保护作用，但其潜在机制尚未得到理解，因此不能推荐食用生牛奶作为过敏性疾病的预防措施。Braun-Fahrlander和E.冯Mutius，临床与实验过敏，2011（41）29-35。
P>Cow's milk is an important part of human diet and a source of food allergy for some individuals. Medical guidance strongly discourages consumption of raw milk because of the known health risk associated with pathogenic bacteria present in unpasteurized milk. Despite these risks there is a growing body of epidemiological evidence suggesting that consumption of unprocessed cow's milk does not increase but rather decreases the risk of asthma, hay fever and atopic sensitisation. The article reviews the epidemiological literature and discusses components of unprocessed milk potentially responsible for this protection. It focuses on the role of bacteria in raw milk, the fatty acid profile, whey proteins and finally the role of allergens in milk. Although the epidemiological evidence consistently suggest a protective role of unprocessed cow's milk consumption on the development of asthma, hay fever and atopic sensitization the underlying mechanisms are not yet understood and the consumption of raw milk cannot be recommended as a preventive measure for allergic diseases.Cite this as: C. Braun-Fahrlander and E. von Mutius, Clinical & Experimental Allergy, 2011 (41) 29-35.