Phosphorylation of the tight-junction protein ZO-1 in two strains of Madin-Darby canine kidney cells which differ in transepithelial resistance.
Phosphorylation of the tight-junction protein ZO-1 in two strains of Madin-Darby canine kidney cells which differ in transepithelial resistance.
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DOI：
10.1042/bj2630597
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发表时间：
1989-10
期刊：
影响因子：
--
通讯作者：
B R Stevenson;J M Anderson;I D Braun;M S Mooseker
中科院分区：
文献类型：
--
作者：
B R Stevenson;J M Anderson;I D Braun;M S Mooseker
比较了两种不同的Madin-Darby犬肾细胞中紧密连接特异性蛋白ZO-1的磷酸盐含量，这是反映紧密连接通透性的参数。分析表明，来自低抗性菌株的ZO-1含有的磷酸盐大约是来自高抗性菌株的两倍。
A comparison was made of the phosphate content of the tight-junction-specific protein ZO-1 in two strains of Madin-Darby canine kidney cells which differ in transepithelial resistance, a parameter reflective of tight-junctional permeability. Analysis revealed that the ZO-1 from the low-resistance strain contained approximately twice as much phosphate as that from the high-resistance strain.