Putting the K+ in K+aloric Restriction.
Putting the K+ in K+aloric Restriction.
复制标题
将 K 置于 K 热量限制中。
DOI:
10.1016/j.immuni.2019.04.016
复制
发表时间:
2019
期刊:
影响因子:
32.4
通讯作者:
VanderHeiden,MatthewG
中科院分区:
文献类型:
--
作者:
Lien,EvanC;Lau,AllisonN;VanderHeiden,MatthewG
Metabolic changes affect T lymphocyte function, and understanding this phenomenon could improve immunotherapy. In a recent paper inScience, Vodnala et al. (2019) report that tumor microenvironmental potassium impairs T cell nutrient uptake and thus causes functional caloric restriction and allows improved anti-tumor immune responses.