Involvement of the subthalamic nucleus and globus pallidus internus in attention
Involvement of the subthalamic nucleus and globus pallidus internus in attention
复制标题
DOI：
10.1007/s00702-010-0575-4
复制
发表时间：
2011-08-01
影响因子：
3.3
通讯作者：
Rektor, I.
中科院分区：
文献类型：
--
作者：
Bockova, M.;Chladek, J.;Rektor, I.
我们研究了认知事件相关电位(ERPs)和事件相关去/同步(ERD/S)在丘脑底核和苍白内球的出现。我们特别关注罕见的非目标(分心)刺激的加工。对7例帕金森病患者和1例植入脑深部刺激电极的原发性肌张力障碍患者的α、β频段的ERPs和ERD/S进行了分析。采用视觉三刺激方案(频繁刺激、靶刺激和分心物)。非靶点和分心物相关的波形表现出相似的形状。在6例帕金森病患者和1例原发性肌张力障碍患者的GPI中，在STN检测到一个200ms左右的特异性正ERP峰和一个低频率的α-ERS，作为对牵张刺激的反应。这种积极可能反映了对分心刺激的注意力定向反应。STN和GPI可能参与注意脑网络。
We studied the appearance of cognitive event-related potentials (ERPs) and event-related de/synchronizations (ERD/S) in the subthalamic nucleus (STN) and globus pallidus internus (GPi). We particularly focused on the rare non-target (distractor) stimuli processing. ERPs and ERD/S in the alpha and beta frequency range were analyzed in seven Parkinson's disease patients and one primary dystonia patient with implanted deep brain stimulation (DBS) electrodes. A visual three-stimulus protocol was used (frequent stimulus, target stimulus, and distractor). The non-target and distractor-related waveforms manifested similar shapes. A specific positive ERP peak around 200 ms and a low alpha frequency ERS were detected from the STN as a response to the distractor stimuli in six of the patients with Parkinson's disease and also in the primary dystonia patient's GPi. This positivity probably reflects an attentional orienting response to the distractor stimuli. The STN and GPi are probably involved in attentional cerebral networks.