The complete phosphotransferase system in Escherichia coli.
The complete phosphotransferase system in Escherichia coli.
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DOI：
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发表时间：
2001-07
影响因子：
1.2
通讯作者：
J. Tchieu;Norris;J. Edwards;M. Saier
中科院分区：
文献类型：
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作者：
J. Tchieu;Norris;J. Edwards;M. Saier
我们在这里列出并描述了所有目前公认的磷酸烯醇丙酮酸：糖磷酸转移酶系统（PTS）的蛋白质及其同源物编码的基因组测序的大肠杆菌。大肠杆菌菌株。有五个公认的酶I同源物和六个公认的HPr同源物。一个氮代谢PTS磷酰基转移链编码内的rpoN和ptsP操纵子和一个三域调节PTS蛋白编码内的dha（二羟丙酮分解代谢）操纵子，可能专门担任监管角色。除了几个额外的推定的调节蛋白，有21（可能22）公认的酶II复合物。在21种酶II复合物中，7种属于果糖（Fru）家族，7种属于葡萄糖（Glc）家族，7种属于其他PTS通透酶家族。所有这些蛋白质的简要描述，并提出了主要家庭的系统发育数据。
We here tabulate and describe all currently recognized proteins of the phosphoenolpyruvate:sugar phosphotransferase system (PTS) and their homologues encoded within the genomes of sequenced E. coli strains. There are five recognized Enzyme I homologues and six recognized HPr homologues. A nitrogen-metabolic PTS phosphoryl transfer chain encoded within the rpoN and ptsP operons and a tri-domain regulatory PTS protein encoded within the dha (dihydroxyacetone catabolic) operon, probably serve regulatory roles exclusively. In addition to several additional putative regulatory proteins, there are 21 (and possibly 22) recognized Enzyme II complexes. Of the 21 Enzyme II complexes, 7 belong to the fructose (Fru) family, 7 belong to the glucose (Glc) family, and 7 belong to the other PTS permease families. All of these proteins are briefly described, and phylogenetic data for the major families are presented.