An evaluation in the diabetes clinic of the Cholestech L‐D‐X analyser
An evaluation in the diabetes clinic of the Cholestech L‐D‐X analyser
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Cholestech L-D-X 分析仪在糖尿病诊所的评估
DOI：
10.1002/pdi.1960110406
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发表时间：
1994
期刊：
影响因子：
--
通讯作者：
B. Slavin
中科院分区：
文献类型：
--
作者：
M. Cummings;G. Watts;J. Mazurkiewicz;B. Slavin
Cholestech L-D-X血脂分析仪（LDX）是第一款用于测定血清高密度脂蛋白胆固醇（HDL-C）浓度的全自动台式分析仪之一，HDL-C浓度是评估血脂异常的重要指标，特别是在非胰岛素依赖型糖尿病患者中。我们比较了总胆固醇（TC），甘油三酯（TG）和HDL-C浓度测定的LDX和标准（DAX）实验室分析仪从40例糖尿病患者的血清中获得的结果。测量浓度之间的平均差异无统计学显著性，方法之间存在非常密切的相关性（TC：LDX = 0.98）。DAX + 0.06，r = 0.98，p<0.01; TG：LDX = 1.01。HDL-C：LDX = DAX +0.03，r = 0.97，p<0.01）。通过方差分析评估的随机误差是最小的。我们的结论是，Cholestech L-D-X分析仪可能是有用的，提供快速和准确的测量血脂谱，特别是在患者中，测量HDL-C浓度是重要的。LDX的体积小、分析速度快和使用简单，使其成为糖尿病诊所和血脂门诊的理想仪器。
The Cholestech L-D-X lipid analyser (LDX) is one of the first fully automated desktop analysers to determine serum high-density-lipoprotein cholesterol (HDL-C) concentration, an important measurement for assessing dyslipidaemia, particularly in patients with non-insulin-dependent diabetes mellitus. We compared results of total cholesterol (TC), triglyceride (TG) and HDL-C concentrations measured by the LDX and by a standard (DAX) laboratory analyser from serum obtained from 40 patients in our diabetic clinic. The mean differences between the concentrations measured were not statistically significant, there being a very close correlation between methods (TC: LDX = 0.98. DAX + 0.06, r = 0.98, p<0.01; TG: LDX = 1.01. DAX + 0.05, r = 0.99, p<0.01 and HDL -C: LDX = DAX + 0.03, r = 0.97, p<0.01). Random error assessed by analysis of variance was minimal. We conclude that the Cholestech L-D-X analyser may be useful for providing rapid and accurate measurements of serum lipid profiles, particularly in patients in whom measuring HDL-C concentration is important. The small size, speed of analysis and simplicity of use of the LDX make it an ideal instrument for utilisation in the diabetes clinic and lipid out-patient clinic.
血液胆固醇浓度：指尖血浆与静脉血清采样。
影响因子：
9.3
作者：
Greenland,P;Bowley,NL;Meiklejohn,B;Doane,KL;Sparks,CE
通讯作者：
Sparks,CE