Uterine Fibroids: Assessing Unmet Needs from Bench to Bedside.
Uterine Fibroids: Assessing Unmet Needs from Bench to Bedside.
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DOI：
10.1089/jwh.2021.0280
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发表时间：
2021-08
期刊：
影响因子：
--
通讯作者：
Laitner MH
中科院分区：
文献类型：
--
作者：
Aninye IO;Laitner MH
子宫肌瘤(肌瘤)是一种非癌性生长，会对数百万女性的健康和生活质量产生有害影响。已尝试更好地了解影响与肌瘤相关的患病率和差异的因素；然而，巨大的知识差距继续存在，这阻碍了对肌瘤患者的护理。妇女健康研究学会召集了一个跨学科的子宫肌瘤工作组，以审查关于子宫肌瘤的当前知识状况，并建议在哪些领域优先努力填补研究差距，改善这种慢性病患者的诊断、治疗和获得护理的机会。在为期两天的圆桌会议上，与会者讨论了有关子宫肌瘤的关键文献、研究、临床实践和公共卫生数据的最新情况。会议结束时，与会者以协商一致的方式确定和确定了总体主题和建议。需要对子宫肌瘤的病因学和病理学进行系统研究，以解决有关肌瘤的多方面治疗及其对整体健康和生活质量的影响方面的重要知识空白和未得到满足的临床需求。工作组建议解决研究、临床护理和联邦政策领域的主要赤字问题。迫在眉睫的需要包括增加研究投资，改进使用盆腔成像对肌瘤的评估，实施纵向研究设计，解决导致疾病差异的因素(特别是有色人种妇女)，开发有利于生育的治疗方案，扩大妇科专家以外的认识和教育，以及通过共享决策方法推进个性化患者护理。
Uterine fibroids (leiomyomas) are noncancerous growths that can have deleterious effects on the health and quality of life for millions of women. Attempts to better understand the factors that influence prevalence and disparities associated with fibroids have been made; however, significant knowledge gaps continue to persist, which hinder care for individuals living with fibroids. The Society for Women's Health Research convened an interdisciplinary Uterine Fibroids Working Group to review the current state of knowledge about uterine fibroids and recommend areas in which to prioritize efforts to address research gaps and improve diagnosis, treatment, and access to care for patients with this chronic disease. Throughout a 2-day roundtable meeting, participants discussed updates on key literature, research, clinical practice, and public health data on uterine fibroids. Overarching themes and recommendations were identified and determined by consensus agreement of the participants at the conclusion of the meeting. Systematic studies of the etiology and pathology of uterine fibroids are needed to address important knowledge gaps and unmet clinical needs regarding the multifaceted management of fibroids and their effects on overall health and quality of life. The Working Group recommends addressing key deficits within the spheres of research, clinical care, and federal policy. Immediate needs include increasing research investment, improving fibroid assessment using pelvic imaging, implementing longitudinal study designs, addressing factors that contribute to disease disparities (especially among women of color), developing fertility-friendly treatment options, expanding awareness and education beyond gynecologic specialists, and advancing personalized patient care through shared decision-making approaches.
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影响因子：
10.4
作者：
D'Aloisio, Aimee A.;Baird, Donna D.;Sandler, Dale P.
通讯作者：
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DOI：
10.1073/pnas.0503218102
发表时间：
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影响因子：
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