Liver Ablation: Best Practice.

Liver Ablation: Best Practice.
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DOI:
10.1016/j.rcl.2015.05.012
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发表时间:
2015-09
影响因子:
1.9
通讯作者:
Lee FT Jr
Lee FT Jr
中科院分区:
医学4区
文献类型:
--
作者:
Wells SA;Hinshaw JL;Lubner MG;Ziemlewicz TJ;Brace CL;Lee FT Jr

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Tumor ablation is broadly defined as the destruction of focal tumors by direct application of chemicals or energy. 1 Tumor ablation therapies are delivered via needlelike applicators and can be broadly categorized into systems based on chemical (primarily ethanol and acetic acid) and thermal or nonthermal energy. The most widely applied thermal ablation modalities in the liver include radiofrequency (RF), microwave (MW), laser, cryoablation, and high-intensity focused ultrasonography (US). Irreversible electroporation (IRE) is generally classified as a nonthermal ablative modality, although cytotoxic temperatures can be achieved with IRE depending on the parameters used during treatment. 2–4Tumor ablation in the liver has evolved to become a well-accepted tool in the management of increasingly complex oncologic patients. Ablative therapies can be used alone, in conjunction with other ablative therapies, or in combination with other oncologic treatment strategies, such as surgery, neoadjuvant and adjuvant chemotherapy, external beam and stereotactic body radiotherapy (SBRT), and arterial liver-directed therapies, including bland embolization, chemoembolization, and/or radioembolization in the treatment of both primary and secondary hepatic malignancies. 5–9
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