Increased Mortality in Bulimia Nervosa and Other Eating Disorders

Increased Mortality in Bulimia Nervosa and Other Eating Disorders
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DOI:
10.1176/appi.ajp.2009.09020247
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发表时间:
2009-12-01
影响因子:
17.7
通讯作者:
Mitchell, James E.
Mitchell, James E.
中科院分区:
医学1区
文献类型:
--
作者:
Crow, Scott J.;Peterson, Carol B.;Mitchell, James E.

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目的:神经性厌食症一直与死亡率增加有关,但这是否适用于其他类型的饮食失调尚不清楚。本研究的目的是确定神经性厌食症、神经性贪食症和饮食失调是否与全因死亡率或自杀死亡率增加有关。方法:使用计算机记录与国家死亡指数的联系,作者对1,885名神经性厌食症患者(N=177)在8至25年内的死亡率进行了纵向评估,结果:神经性厌食症、神经性贪食症和饮食失调的粗死亡率分别为4.0%、3.9%和5.2%。神经性贪食症和进食障碍的全因标准化死亡率显着升高,自杀的标准化死亡率升高神经性贪食症和进食障碍,否则specified.Conclusions:个人与进食障碍,否则specified. This有时被视为“不太严重”的进食障碍,有升高的死亡风险,类似于神经性厌食症。这项研究还表明,在饮食失调诊断中自杀的风险增加。
Objective: Anorexia nervosa has been consistently associated with increased mortality, but whether this is true for other types of eating disorders is unclear. The goal of this study was to determine whether anorexia nervosa, bulimia nervosa, and eating disorder not otherwise specified are associated with increased all-cause mortality or suicide mortality.Method: Using computerized record linkage to the National Death Index, the authors conducted a longitudinal assessment of mortality over 8 to 25 years in 1,885 individuals with anorexia nervosa (N=177), bulimia nervosa (N=906), or eating disorder not otherwise specified (N=802) who presented for treatment at a specialized eating disorders clinic in an academic medical center.Results: Crude mortality rates were 4.0% for anorexia nervosa, 3.9% for bulimia nervosa, and 5.2% for eating disorder not otherwise specified. All-cause standardized mortality ratios were significantly elevated for bulimia nervosa and eating disorder not otherwise specified; suicide standardized mortality ratios were elevated for bulimia nervosa and eating disorder not otherwise specified.Conclusions: Individuals with eating disorder not otherwise specified, which is sometimes viewed as a "less severe" eating disorder, had elevated mortality risks, similar to those found in anorexia nervosa. This study also demonstrated an increased risk of suicide across eating disorder diagnoses.