Microcystic adnexal carcinoma associated with primary immunodeficiency, recurrent diffuse herpes simplex virus infection, and cutaneous T-cell lymphoma
Microcystic adnexal carcinoma associated with primary immunodeficiency, recurrent diffuse herpes simplex virus infection, and cutaneous T-cell lymphoma
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DOI：
10.1097/00000372-200012000-00008
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发表时间：
2000-12-01
影响因子：
1.1
通讯作者：
Duray, PH
中科院分区：
文献类型：
--
作者：
Lei, JY;Wang, Y;Duray, PH
皮肤微囊性附属器癌(MAC)是一种罕见且鲜为人知的肿瘤，主要发生在头颈部。Mac通常会影响四五十岁的人。一些患者有过放射史。我们报告一例发生在左肘前窝的罕见免疫缺陷综合症的18岁白人女性。患者还发生了鳞状细胞癌、皮肤T细胞恶性肿瘤和胃周肌瘤。先天性单纯疱疹病毒(HSV)感染持续了她的一生。讨论了HSV感染与MAC和鳞癌的关系，以及外周T细胞淋巴瘤与Epstein-Barr病毒感染的关系，以及与Her免疫缺陷的关系。
Cutaneous microcystic adnexal carcinoma (MAC) is a rare and poorly understood tumor that predominantly occurs in the head and neck. MAC usually affects people in their fourth and fifth decades. Some patients have had a history of radiation. We present a case of MAC occurring in the left antecubital fossa of an 18-year-old white woman with an unusual immunodeficiency syndrome. The patient also developed a squamous cell carcinoma, a cutaneous T-cell malignancy, and a perigastric leiomyoma. A congenital infection of herpes simplex virus (HSV) persisted throughout her life. The association of HSV infection with MAC and squamous cell carcinoma and that of peripheral T-cell lymphoma with Epstein-Barr virus is discussed in relation to her immunodeficiency.