Moderate neonatal encephalopathy:: Pre- and perinatal risk factors and long-term outcome
Moderate neonatal encephalopathy:: Pre- and perinatal risk factors and long-term outcome
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DOI：
10.1080/00016340801996622
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发表时间：
2008-01-01
影响因子：
4.3
通讯作者：
Westgren, Magnus
中科院分区：
文献类型：
--
作者：
Lindstrom, Katarina;Hallberg, Boubou;Westgren, Magnus
背景目的是描述足月出生的5分钟Apgar评分< 7分和中度新生儿脑病的儿童的产前和围产期数据和长期神经发育结局（15 - 19岁）。方法.这项研究是基于1985年在瑞典出生的儿童的人口出生队列。对产妇、分娩、新生儿和神经儿科数据进行了汇编。神经发育状态根据1.脑性瘫痪或其他重大损伤，2。完全认知障碍，以及3.没有损伤结果大多数儿童（81%）有认知功能障碍，有或没有其他障碍，如脑瘫。过期分娩率（19%对8%）和臀位（12%对3%）明显高于瑞典一般人群。产前和围产期数据在三个结局组之间没有显著差异。可疑或次优产科护理是常见的（55%）。结论.该研究表明，在长期随访中，患有中度新生儿脑病的足月出生儿童有很高的认知功能障碍率，无论是否患有脑瘫。我们的产前和围产期数据与结果无关。
Background. The aim was to describe pre- and perinatal data and long-term neurodevelopmental outcome (15 - 19 years) in children born at term with Apgar score < 7 at 5 min and moderate neonatal encephalopathy. Methods. The study is based on a population-based birth-cohort of children born in Sweden in 1985. Maternal, delivery, neonatal, and neuropaediatric data were compiled. Neurodevelopmental status was classified according to the presence of 1. cerebral palsy or other major impairments, 2. exclusively cognitive impairments, and 3. no impairments. Results. The majority of the children (81%) had cognitive dysfunctions, with or without other impairments, such as cerebral palsy. The rates of post-term birth (19% versus 8%) and breech presentation (12% versus 3%) were significantly higher than in the general Swedish population. Pre- and perinatal data did not differ notably between the three outcome groups. Questionable or suboptimal obstetric care was common (55%). Conclusions. The study shows that children born at term with moderate neonatal encephalopathy have a high rate of cognitive dysfunctions with or without cerebral palsy at long-term follow-up. Our pre- and perinatal data did not correlate with outcome.