Rickets
Rickets
复制标题
DOI：
10.1016/s0140-6736(13)61650-5
复制
发表时间：
2014-05-10
期刊：
影响因子：
168.9
通讯作者：
Bishop, Nicholas J.
中科院分区：
文献类型：
--
作者：
Elder, Charlotte Jane;Bishop, Nicholas J.
佝偻病在历史上被称为“英国病”，在世界范围内很常见。生长板缺乏磷酸盐和矿化骨表面由于维生素D供应不足，无论是从阳光照射或饮食是主要原因。引起低磷血症的遗传性疾病显示了磷酸盐代谢的复杂性。目前关于向幼儿提供维生素D的建议需要澄清;现有的指导是支离破碎和相互矛盾的，无助于根除这种疾病。
Rickets, historically referred to as "the English disease", is common worldwide. Absence of phosphate at the growth plate and mineralising bone surfaces due to inadequate vitamin D supply either from sunlight exposure or diet is the main cause. Inherited disorders causing hypophosphataemia have shown the intricacies of phosphate metabolism. Present advice about the provision of vitamin D to young infants needs to be clarified; the existing guidance is fragmentary and contradictory, and will not help to eradicate the disease.