Relationship between blood levels of N-carboxymethyl-lysine and pentosidine and the severity of microangiopathy in type 2 diabetes
Relationship between blood levels of N-carboxymethyl-lysine and pentosidine and the severity of microangiopathy in type 2 diabetes
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DOI：
10.1507/endocrj.51.537
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发表时间：
2004-12-01
影响因子：
2
通讯作者：
Kubo, K
中科院分区：
文献类型：
--
作者：
Hirata, K;Kubo, K
研究了2型糖尿病患者血中N-羧甲基赖氨酸（CML）和戊糖甙水平与微血管病变严重程度的关系。用酶联免疫吸附试验（ELISA）测定97例2型糖尿病患者（男46例，女51例）血CML和戊糖甙水平。慢性肾功能衰竭患者的CML和戊糖苷酶水平显著高于正常白蛋白尿、微量白蛋白尿或大量白蛋白尿患者（均P
The relationship between blood levels of N-carboxymethyl-lysine (CML) or pentosidine and the severity of microangiopathy was investigated in patients with type 2 diabetes. Blood CML and pentosidine levels were measured by ELISA in 97 type 2 diabetics (46 men and 51 women). CML and pentosidine levels were significantly higher in patients with chronic renal failure than in those with normoalbuminuria, microalbuminuria, or macroalbuminuria (all p