A Strategy for Depositing Different Types of Cells in Three Dimensions to Mimic Tubular Structures in Tissues
A Strategy for Depositing Different Types of Cells in Three Dimensions to Mimic Tubular Structures in Tissues
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DOI：
10.1002/adma.201104589
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发表时间：
2012-02
影响因子：
29.4
通讯作者：
Bo Yuan;Yu Jin;Yi Sun;Dong Wang;Jiashu Sun;Zhuo Wang;Wei Zhang-;Xingyu Jiang
中科院分区：
文献类型：
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作者：
Bo Yuan;Yu Jin;Yi Sun;Dong Wang;Jiashu Sun;Zhuo Wang;Wei Zhang-;Xingyu Jiang
使用应力诱导滚动膜（SIRM）描述了管状结构的制造，其中多种细胞类型形成管壁的不同层。管内部的细胞取向也可以通过形貌接触引导来控制。这些层状管精确地模仿血管和许多其他管状结构，这表明它们可能在组织工程中有很大的用途。
The fabrication of tubular structures, with multiple cell types forming different layers of the tube walls, is described using a stress-induced rolling membrane (SIRM). Cell orientation inside the tubes can also be controlled by topographical contact guidance. These layered tubes precisely mimic blood vessels and many other tubular structures, suggesting that they may be of great use in tissue engineering.