Histopathology of Alcohol-Related Liver Diseases
Histopathology of Alcohol-Related Liver Diseases
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DOI：
10.1016/j.cld.2018.09.001
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发表时间：
2019-02-01
影响因子：
5.1
通讯作者：
Qin, Jia
中科院分区：
文献类型：
--
作者：
Roth, Nitzan C.;Qin, Jia
Excessive alcohol consumption can lead to a spectrum of liver histopathology, including steatosis, steatohepatitis, foamy degeneration, fatty liver with cholestasis, and cirrhosis. Although variability in sampling and pathologist interpretation are of some concern, liver biopsy remains the gold standard for distinguishing between steatohepatitis and noninflammatory histologic patterns of injury that can also cause the clinical syndrome of alcohol-related hepatitis. Liver biopsy is not routinely recommended to ascertain a diagnosis of alcohol-related liver disease in patients with an uncertain alcohol history, because the histologic features of alcohol-related liver diseases can be found in other diseases, including nonalcoholic steatohepatitis and drug-induced liver injury.
