The role of anaerobic bacteria in tonsillitis
The role of anaerobic bacteria in tonsillitis
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DOI：
10.1016/j.ijporl.2004.08.007
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发表时间：
2005-01-01
影响因子：
1.5
通讯作者：
Brook, I
中科院分区：
文献类型：
--
作者：
Brook, I
这篇综述总结了支持厌氧菌在扁桃体炎中潜在重要性的信息。一些厌氧菌具有干扰 A 族 β 溶血性链球菌 (GABHS) 和其他病原体的能力。厌氧菌在扁桃体急性炎症过程中的可能作用得到了多项观察结果的支持：厌氧菌已从复发性 GABHS 和非 GABHS 扁桃体炎 (NST) 患者的扁桃体核心中分离出来；厌氧菌恢复为扁桃体脓肿中的主要病原体，在许多情况下没有任何需氧菌；它们作为扁桃体厌氧菌感染（文森特心绞痛）中的病原体而恢复，封装的色素普雷沃氏菌和卟啉单胞菌的恢复率提高。扁桃体急性发炎；它们与复发性 NST 炎症核心的分离：以及 NST 患者对抗生素的反应 此外，复发性 NST 患者中存在针对中间普雷沃氏菌的免疫反应，在从扁桃体周围蜂窝织炎或脓肿、传染性单核细胞增多症和急性扁桃体周围脓肿恢复的患者中也可以检测到针对中间普雷沃氏菌和具核梭杆菌的免疫反应。 非链球菌和 GABHS 扁桃体炎。尽管还需要更多的研究，但这些发现支持革兰氏阴性厌氧杆菌对扁桃体炎的可能致病性。由爱思唯尔爱尔兰有限公司出版
This review summarizes the information that supports the potential importance of anaerobic bacteria in tonsillitis. Some anaerobic bacteria possess interfering capability with Group A beta-hemolytic streptococci (GABHS) and other pathogens. The possible role of anaerobes in the acute inflammatory process in the tonsils is supported by several observations: anaerobes have been isolated from the cores of tonsils of patients with recurrent GABHS and non-GABHS tonsillitis (NST); the recovery of anaerobes as predominant pathogens in abscesses of tonsils, in many cases without any aerobic bacteria; their recovery as pathogens in well-established anaerobic infections of the tonsils (Vincent's angina), the increased recovery rate of encapsulated pigmented Prevotella and Porphyromonas spp. in acutely inflamed tonsils; their isolation from the cores of recurrently inflamed NST: and the response to antibiotics in patients with NST Furthermore, immune response against Prevotella intermedia is present in patients with recurrent NST and an immune response can also be detected against P. intermedia and Fusobacterium nucleatum in patients who recovered from peritonsillar cellulitis or abscesses, infectious mononucleosis and acute non-streptococcal and GABHS tonsillitis. Although more studies are needed, these findings support the possible pathogenicity of Gram-negative anaerobic bacilli in tonsillitis. Published by Elsevier Ireland Ltd.