GASTRIC SECRETION DURING PREGNANCY AND LACTATION IN RAT
GASTRIC SECRETION DURING PREGNANCY AND LACTATION IN RAT
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DOI：
10.1113/jphysiol.1967.sp008206
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发表时间：
1967-01-01
影响因子：
5.5
通讯作者：
SVENSSON, SE
中科院分区：
文献类型：
--
作者：
LILJA, B;SVENSSON, SE
用不同类型的胃制剂对妊娠前后大鼠胃酸分泌进行了研究。同时测定了胃黏膜和乳腺的组胺形成能力（HFC）。全胃瘘大鼠在妊娠和哺乳期消化间酸分泌增加。在无神经支配的大鼠慢性眼袋分泌对胃泌素和组胺刺激的反应在妊娠和哺乳期增强。胃黏膜组胺形成能力（HFC）在妊娠后期和哺乳期增加2-3倍。与妊娠期发育完全的乳腺相比，哺乳期乳腺的HFC增加2-3倍。
Gastric acid secretion has been studied in the rat before, during and after pregnancy using different types of stomach preparation. During the same periods the histamine-forming capacity (HFC) has been determined in gastric mucosa and mammary gland. In rats with a whole stomach fistula interdigestive acid secretion is increased during pregnancy and lactation. In rats with a denervated chronic pouch secretory response to stimulation with gastrin and histamine is augmented during pregnancy and lactation. The histamine forming capacity (HFC) of the gastric mucosa is increased 2-3 times during the last days of pregnancy and also during lactation. The HFC of the mammary gland is increased 2-3 times during lactation as compared with the fully developed gland in pregnancy.