Structural changes in synthetic myosin minifilaments and their dissociation by adenosine triphosphate and pyrophosphate.
Structural changes in synthetic myosin minifilaments and their dissociation by adenosine triphosphate and pyrophosphate.
复制标题
合成肌球蛋白微丝的结构变化及其三磷酸腺苷和焦磷酸的解离。
DOI:
10.1021/bi00507a002
复制
发表时间:
1981
期刊:
影响因子:
2.9
通讯作者:
Reisler,E
中科院分区:
文献类型:
--
作者:
Oriol-Audit,C;Lake,JA;Reisler,E
Identical binding of these ligands to myosin and rod minifi-laments suggests that myosin heads play no role in substrate-induced destabilization of the minifilaments. The effects of ATP and pyrophosphate on minifilaments are similar to their dissociating effect on synthetic filaments [Harrington, W. F., & Himmelfarb, S.(1972) Biochemistry 11, 2945-2952], thus justifying their use in conformational studies