The promise of receptor studies in psychophysiologic research.
The promise of receptor studies in psychophysiologic research.
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受体研究在心理生理学研究中的前景。
DOI：
10.1097/00006842-198811000-00001
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发表时间：
1988
影响因子：
3.3
通讯作者：
Dimsdale,JE
中科院分区：
文献类型：
--
作者：
Mills,PJ;Dimsdale,JE
大多数关于应激反应的研究都局限于应激反应的神经激素和心血管成分。然而，还有另一个调查领域对这一领域具有重要意义。受体结合技术提供了神经激素信号和它们所刺激的反应之间的功能联系的直接测量。受体测量将使心理生理学研究能够开始解决构成所有反应模式的信号发射/接收/末端器官反应的完整三位一体。本文综述了肾上腺素能受体的生理、方法及相关研究进展。我们的目的是鼓励在反应性研究中更多地考虑这些重要问题。
Most research on reactivity to stressors limits its focus to the neurohormonal and cardiovascular components of reactivity. There is, however, another area of investigation with important implications to this field. Receptor binding techniques provide a direct measure of the functional link between neurohormonal signals and the responses they stimulate. Receptor measurement would enable psychophysiologic studies to begin to address the complete triad of signal emission/reception/end-organ response that underlies all reactivity patterns. This paper reviews adrenergic receptor physiology, methods, and research pertinent to reactivity. Our intention is to encourage greater consideration of these important issues in reactivity research.